关键信息
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基因名
FOXA3
- 应用
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别名
FOXA3；HNF3G；TCF3G；Hepatocyte nuclear factor 3-gamma
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P55318
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表达区间
2-350aa
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氨基酸序列
29 amino acid tag-GEFLGSVKMEAHDLAEWSYYPEAGEVYSPVTPVPTMAPLNSYMTLN PLSSPYPPGGLPASPLPSGPLAPPAPAAPLGPTFPGLGVSGGSSSSGYGA PGPGLVHGKEMPKGYRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIY QWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALH PSSGNMFENGCYLRRQKRFKLEEKVKKGGSGAATTTRNGTGSAASTTTPA ATVTSPPQPPPPAPEPEAQGGEDVGALDCGSPASSTPYFTGLELPGELKL DAPYNFNHPFSINNLMSEQTPAPPKLDVGFGGYGAEGGEPGVYYQGLYSR SLLNASLEESGGGGSPGRRRRRRRRRRR
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分子量
37 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
FOXA3, a member of the Forkhead box (Fox) transcription factor family, plays a crucial role in various biological processes, including organogenesis, metabolism, and cellular differentiation. Research into FOXA3 has intensified due to its significant involvement in the regulation of genes associated with lipid metabolism and glucose homeostasis, making it a potential target for therapeutic interventions in metabolic disorders such as obesity and type 2 diabetes. The recombination and expression of FOXA3 protein allow scientists to explore its functional mechanisms in detail. By utilizing recombinant FOXA3, researchers can investigate its role in transcriptional regulation and its interactions with other cellular pathways. Understanding the structure-function relationship of FOXA3 can provide insights into its regulatory mechanisms and its potential implications in disease contexts. Moreover, the study of FOXA3 in relation to environmental factors, such as diet and lifestyle, is of growing interest, as it can illuminate the gene’s role in adaptive responses and metabolic flexibility. As the prevalence of metabolic diseases continues to rise globally, the elucidation of FOXA3’s molecular pathways offers promising avenues for novel therapeutic strategies, highlighting the importance of ongoing research in this field.
