关键信息
-
基因名
SMCP
- 应用
-
别名
SMCP;MCS;MCSP;Sperm mitochondrial-associated cysteine-rich Protein
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P49901
-
表达区间
1-116aa
-
氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMCDQTKH SKCCPAKGNQ CCPPQQNQCC QSKGNQCCPP KQNQCCQPKG SQCCPPKHNH CCQPKPPCCI QARCCGLETK PEVSPLNMES EPNSPQTQDK GCQTQQQPHS PQNESRPSK
-
分子量
15 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
SMCP, or Sperm Microtubule-Associated Protein, has garnered significant interest in the field of reproductive biology and cell motility due to its unique structure and function. This protein is crucial for sperm maturation and motility, influencing the interaction between microtubules and sperm flagella. Studies have shown that SMCP plays a pivotal role in the assembly and stabilization of the axoneme—a fundamental structural component of the flagellum—contributing to the efficient movement of sperm. Investigating the molecular mechanisms behind SMCP's function helps to uncover the intricacies of sperm biology and potential fertility issues. Additionally, mutations or dysregulation of SMCP may lead to male infertility, making it a target for potential therapeutic interventions. Research into SMCP not only enhances our understanding of male reproductive health but also offers insights into microtubule dynamics, which are essential in various cellular processes, extending its relevance beyond reproductive systems to broader biological contexts. This growing body of work highlights the need for in-depth studies that could elucidate the functional pathways of SMCP and its interactions within the intricately regulated environment of the sperm cell.
