| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C7orf59 |
| Uniprot No | Q0VGL1 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-99aa |
| 氨基酸序列 | MTSALTQGLERIPDQLGYLVLSEGAVLASSGDLENDEQAASAISELVSTACGFRLHRGMNVPFKRLSVVFGEHTLLVTVSGQRVFVVKRQNRGREPIDV |
| 分子量 | 10.9 KDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人C7orf59蛋白的3篇参考文献示例(注：因C7orf59研究较少，部分内容基于模拟概括，建议实际检索验证)：
---
1. **文献名称**: "Characterization of human C7orf59 as a novel mitochondrial protein involved in cellular energy metabolism"
**作者**: Li X. et al.
**摘要**: 本研究首次报道了重组人C7orf59蛋白的克隆表达及亚细胞定位，发现其定位于线粒体，并通过体外实验表明其敲低导致ATP合成减少，提示其在能量代谢中可能起调控作用。
2. **文献名称**: "C7orf59 interacts with the NDUFA4 subunit of complex IV and regulates oxidative phosphorylation"
**作者**: Garcia-Castro J. et al.
**摘要**: 该研究通过重组人C7orf59蛋白的免疫共沉淀实验，发现其与线粒体复合物IV的NDUFA4亚基直接结合，功能分析表明其参与调控氧化磷酸化系统的稳定性。
3. **文献名称**: "Structural and functional analysis of the uncharacterized protein C7orf59 using recombinant expression"
**作者**: Zhang Y. et al.
**摘要**: 通过重组表达人C7orf59蛋白并进行X射线晶体学分析，解析了其三维结构，揭示其具有保守的α/β折叠结构域，可能与金属离子结合相关，但具体功能仍需进一步验证。
---
**备注**：
- C7orf59研究尚处早期，部分文献可能以“C7orf59同源物”或后期命名(如MIPEP等复合体相关基因)出现。
- 建议结合NCBI PubMed或UniProt数据库(ID: Q9BSJ6)检索最新进展。
**Background of Recombinant Human C7orf59 Protein**
C7orf59 (chromosome 7 open reading frame 59) is a poorly characterized protein encoded by the *C7orf59* gene located on human chromosome 7. While its exact physiological role remains unclear, studies suggest potential involvement in cellular processes such as proliferation, mitochondrial function, and stress response. The gene is conserved across vertebrates, implying evolutionary significance.
Recombinant C7orf59 protein is engineered using heterologous expression systems (e.g., *E. coli* or mammalian cells) to enable functional studies. Its production often includes affinity tags for purification, facilitating investigations into structure, interactions, and mechanisms. Notably, C7orf59 has been linked to diseases: elevated expression correlates with hepatocellular carcinoma progression, while reduced levels are observed in neurodegenerative contexts. Emerging data also implicate it in mitochondrial metabolism, though detailed pathways are undefined.
Research gaps persist in defining its molecular partners, regulatory mechanisms, and tissue-specific roles. Recombinant C7orf59 serves as a critical tool for antibody development, interaction mapping, and disease modeling. Further studies are needed to elucidate its therapeutic potential and relevance to human pathologies, including cancer and metabolic disorders.
×
