关键信息
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基因名
ABI2
- 应用
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别名
Abelson interactor 2; ABI 2; Abi-2; ABI2; ABI2_HUMAN; ABI2B; Abl binding Protein 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NYB9
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表达区间
1-513aa
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氨基酸序列
MAELQMLLEE EIPGGRRALF DSYTNLERVA DYCENNYIQS ADKQRALEET KAYTTQSLAS VAYLINTLAN NVLQMLDIQA SQLRRMESSI NHISQTVDIH KEKVARREIG ILTTNKNTSR THKIIAPANL ERPVRYIRKP IDYTILDDIG HGVKWLLRFK VSTQNMKMGG LPRTTPPTQK PPSPPMSGKG TLGRHSPYRT LEPVRPPVVP NDYVPSPTRN MAPSQQSPVR TASVNQRNRT YSSSGSSGGS HPSSRSSSRE NSGSGSVGVP IAVPTPSPPS VFPAPAGSAG TPPLPATSAS APAPLVPATV PSSTAPNAAA GGAPNLADGF TSPTPPVVSS TPPTGHPVQF YSMNRPASRH TPPTIGGSLP YRRPPSITSQ TSLQNQMNGG PFYSQNPVSD TPPPPPPVEE PVFDESPPPP PPPEDYEEEE AAVVEYSDPY AEEDPPWAPR SYLEKVVAIY DYTKDKEDEL SFQEGAIIYV IKKNDDGWYE GVMNGVTGLF PGNYVESIMH YSE
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分子量
55.6 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
ABI2 (Abelson interactor 2) is a protein involved in various cellular processes, particularly in the regulation of actin cytoskeleton dynamics and cellular signaling pathways. It has garnered interest in the field of cancer research due to its potential role in tumor progression and metastasis. Studies have shown that ABI2 interacts with several key signaling molecules, including those in the Rho GTPase family, which are crucial for cell motility and morphology. Given its involvement in crucial cellular functions, the characterization and functional analysis of ABI2, particularly in its recombinant form, have become essential for understanding its biological roles and regulatory mechanisms. The production of recombinant ABI2 allows for detailed biophysical and biochemical characterization, facilitating studies on its interactions with other proteins and cellular partners. Investigating ABI2's structure-function relationships through recombinant approaches can provide insights into its role in pathophysiological conditions, making it a promising target for therapeutic interventions in diseases where actin dynamics and related signaling pathways are disrupted. Overall, the study of ABI2 as a recombinant protein is vital for elucidating its contributions to cellular processes and its potential implications in cancer biology.
