| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C6orf203 |
| Uniprot No | Q9P0P8 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-240aa |
| 氨基酸序列 | MAMASVKLLAGVLRKPDAWIGLWGVLRGTPSSYKLCTSWNRYLYFSSTKLRAPNYKTLFYNIFSLRLPGLLLSPECIFPFSVRLKSNIRSTKSTKKSLQKVDEEDSDEESHHDEMSEQEEELEDDPTVVKNYKDLEKAVQSFRYDVVLKTGLDIGRNKVEDAFYKGELRLNEEKLWKKSRTVKVGDTLDLLIGEDKEAGTETVMRILLKKVFEEKTESEKYRVVLRRWKSLKLPKKRMSK |
| 分子量 | 54.3 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人C6orf203蛋白的3篇示例参考文献（注：文献为虚构示例，仅供格式参考）：
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1. **文献名称**: *C6orf203 encodes a mitochondrial protein regulating oxidative phosphorylation*
**作者**: Chen Y, et al.
**摘要**: 研究通过重组表达人C6orf203蛋白，证实其定位于线粒体内膜，并参与维持ATP合成酶复合体活性，敲除该基因导致细胞能量代谢异常。
2. **文献名称**: *Recombinant C6orf203 exhibits nucleic acid-binding activity and modulates innate immunity*
**作者**: Tanaka R, et al.
**摘要**: 体外表达并纯化重组C6orf203蛋白，发现其通过结合病毒RNA激活RIG-I信号通路，提示其在抗病毒先天免疫中的潜在作用。
3. **文献名称**: *Structural and functional analysis of the orphan protein C6orf203*
**作者**: Müller S, et al.
**摘要**: 结合冷冻电镜技术解析重组C6orf203的三维结构，揭示其具有类泛素修饰酶结构域，可能参与蛋白质翻译后调控过程。
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**注**：实际研究中，C6orf203的功能尚未完全明确，建议通过PubMed或UniProt数据库检索最新文献（关键词：C6orf203、TXNDC5、AEBP2等别名）。
**Background of Recombinant Human C6orf203 Protein**
C6orf203, also known as chromosome 6 open reading frame 203, is a poorly characterized protein encoded by the *C6orf203* gene in humans. This evolutionarily conserved protein is ubiquitously expressed, with higher levels observed in tissues such as the heart, liver, and skeletal muscle. Structurally, it contains a conserved DUF1518 domain, suggesting potential roles in hydrolytic or nucleotide-binding activities, though its precise biochemical function remains unclear.
Emerging studies implicate C6orf203 in mitochondrial translation and ribosome assembly. It has been proposed to interact with mitochondrial ribosomal proteins, such as MRPL18, potentially influencing mitochondrial protein synthesis and energy metabolism. Additionally, genomic analyses link *C6orf203* to neurodevelopmental disorders and cancers, though mechanistic insights are limited.
Recombinant human C6orf203 protein, produced via heterologous expression systems like *E. coli* or mammalian cells, enables functional and structural studies. Its purified form is used to investigate molecular interactions, subcellular localization, and enzymatic activities. Despite progress, further research is needed to define its physiological roles, regulation, and relevance in disease pathways, highlighting its potential as a target for therapeutic exploration.
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