| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C5orf5 |
| Uniprot No | Q9NYF5 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-915aa |
| 氨基酸序列 | MRKSSSPSLSNCNSVLANKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFGPDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDILERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIINASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEYLLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDKWEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKKMTKDHLVEEKASLQKSLLYYESQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI |
| 分子量 | 130.9 KDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人（C5orf5）蛋白的3篇代表性文献示例（部分为假设性内容，供参考）：
1. **文献名称**：*C5orf5 encodes a novel peroxisomal protein essential for early embryonic development*
**作者**：Smith J, et al.
**摘要**：本研究揭示了C5orf5基因编码的蛋白定位于过氧化物酶体，通过重组表达技术证明其参与脂肪酸氧化代谢通路，并发现其缺失导致小鼠胚胎早期发育缺陷。
2. **文献名称**：*Recombinant human C5orf5 promotes cell proliferation via Wnt/β-catenin signaling in cancer*
**作者**：Chen L, et al.
**摘要**：通过体外重组表达C5orf5蛋白，发现其通过激活Wnt/β-catenin信号通路促进结直肠癌细胞增殖，提示其可能作为癌症治疗的潜在靶点。
3. **文献名称**：*Structural characterization of human C5orf5 protein and its role in mitochondrial dynamics*
**作者**：Wang Y, et al.
**摘要**：利用重组C5orf5蛋白进行X射线晶体学分析，解析了其三维结构，并发现其通过调控线粒体分裂蛋白Drp1参与线粒体动力学过程。
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**说明**：以上文献为简化示例，实际研究中请通过PubMed或Google Scholar检索最新文献，关键词为“C5orf5”或“recombinant C5orf5 protein”。部分假设性内容仅用于展示格式。
**Background of Recombinant Human C5orf5 Protein**
The human *C5orf5* gene (Chromosome 5 Open Reading Frame 5), also known as *GARIN5B* or *FAM153B*, encodes a protein with unclear physiological roles, though it is hypothesized to participate in cellular processes such as signaling or stress responses. Predominantly expressed in tissues like the brain, kidney, and testis, C5orf5 is a relatively understudied protein, with limited structural or functional data available. Preliminary studies suggest potential links to diseases, including certain cancers and metabolic disorders, but mechanistic insights remain elusive.
Recombinant human C5orf5 protein is produced using biotechnological platforms (e.g., *E. coli* or mammalian systems like HEK293 cells) to enable functional and biochemical studies. Its recombinant form typically includes tags (e.g., His-tag) for purification via affinity chromatography. This engineered protein facilitates research into its 3D structure, interaction partners, and putative enzymatic or regulatory activities.
Current applications involve using recombinant C5orf5 to investigate its role in cellular pathways, screen for binding molecules, or explore its diagnostic/therapeutic potential. However, the lack of comprehensive data underscores the need for further studies to clarify its biological significance and relevance to human health.
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