| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C3orf38 |
| Uniprot No | Q8NAT1 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-327aa |
| 氨基酸序列 | MSGLSFSEMEGCRNLLGLLDNDEIMALCDTVTNRLVQPQDRQDAVHAILAYSQSAEELLRRRKVHREVIFKYLATQGIVIPPATEKHNLIQHAKDYWQKQPQLKLKETPEPVTKTEDIHLFQQQVKEDKKAEKVDFRRLGEEFCHWFFGLLNSQNPFLGPPQDEWGPQHFWHDVKLRFYYNTSEQNVMDYHGAEIVSLRLLSLVKEEFLFLSPNLDSHGLKCASSPHGLVMVGVAGTVHRGNTCLGIFEQIFGLIRCPFVENTWKIKFINLKIMGESSLAPGTLPKPSVKFEQSDLEAFYNVITVCGTNEVRHNVKQASDSGTGDQV |
| 分子量 | 63.7 KDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人C3orf38蛋白的示例参考文献（注：以下内容为虚构示例，实际文献需通过学术数据库检索确认）：
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1. **标题**: *"C3orf38 encodes a nucleolar protein involved in ribosome biogenesis"*
**作者**: Smith J, et al.
**摘要**: 研究通过基因表达分析发现，C3orf38定位于细胞核仁，参与核糖体RNA加工，敲除后导致细胞周期停滞，提示其在核糖体组装中的潜在作用。
2. **标题**: *"Recombinant expression and functional analysis of human C3orf38 in cancer cells"*
**作者**: Chen L, et al.
**摘要**: 本文利用大肠杆菌系统重组表达C3orf38蛋白，证实其在乳腺癌细胞中高表达，并通过调控MAPK通路促进肿瘤细胞侵袭。
3. **标题**: *"Structural insights into the C3orf38 protein and its interaction with HSP90"*
**作者**: Gonzalez R, et al.
**摘要**: 通过X射线晶体学解析C3orf38的三维结构，揭示其与分子伴侣HSP90的相互作用，为理解其蛋白稳定性机制提供依据。
4. **标题**: *"C3orf38 deficiency links to mitochondrial dysfunction and neurodegenerative disorders"*
**作者**: Kim H, et al.
**摘要**: 在小鼠模型中，C3orf38缺失导致线粒体膜电位异常和神经元凋亡，提示其与阿尔茨海默病等神经退行性疾病的关联。
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**注意**：以上文献为示例，实际研究中请通过**PubMed**、**Google Scholar**或**Web of Science**等平台检索真实论文（关键词如“C3orf38 function”“recombinant C3orf38”）。若该蛋白研究较少，可扩展至其染色体区域（3p21.3）或邻近基因的调控分析。
**Background of Recombinant Human C3orf38 Protein**
The C3orf38 (Chromosome 3 Open Reading Frame 38) gene, located on the short arm of human chromosome 3 (3p21.31), encodes a protein whose biological functions remain poorly characterized. It is classified as a hypothetical protein due to limited experimental validation, though computational analyses suggest it may possess functional domains linked to nucleic acid binding or enzymatic activity. C3orf38 is evolutionarily conserved across vertebrates, hinting at potential roles in fundamental cellular processes.
Recombinant human C3orf38 protein is artificially expressed in vitro, often using bacterial or eukaryotic systems, to enable functional and structural studies. Its recombinant form allows researchers to investigate its interactions, post-translational modifications, and putative involvement in pathways such as cell cycle regulation or stress responses. Some studies associate C3orf38 with diseases, including cancer, based on differential expression patterns in tumors, though mechanistic insights are lacking.
Despite its unclear physiological role, C3orf38 has drawn interest as a biomarker candidate or therapeutic target due to tissue-specific expression and genetic polymorphisms linked to human disorders. Current research focuses on elucidating its molecular partners and regulatory networks using recombinant protein tools. Further studies are essential to unravel its contribution to cellular homeostasis or pathology, bridging gaps between genomic data and functional annotation.
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