| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C3orf15 |
| Uniprot No | Q7Z4T9 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-767aa |
| 氨基酸序列 | MSHAVTIEEPQAQPQVSQTRYRERSRAGSHISSNRAYDFLYDPLFIVSSEKDHTQANIQATLIRSRLRKVPRFKTMFSNLIHYPRYSLYWSKSDPVPPFISREWKGHKEKHREALRQLTTTDASFQMPKEVYEDPEVTGKNRYKYFERPFLPFFQQMPFNVVYAVSKAEPYTFPPTSTKHLSIPSKSTVGTQTDYRDADVQTDPYSPEYVVCQDSIPELLTLATLTWGRGLPAGQAEVEMIERAREKRAWEASLPALSDTSQFEKRRKMMNEMERKEWAFREQEIEKLQEIRLEVLKELLRKREENQNEVNMKHLNARWSKLQEGKEAKMAKIQRTHVSTIRKLVGKRKNIEGKLERRNIIKDYSDYASQVYGPLSRLGCFPDNNSEDFVVKNYYLNTYEGLVELESCLPDFVTQPQIRAPKPKVITTKAGFLKRAARLDYELAEVHKALLDKKNKVLEVKKPPRFLQRNPIPQPRLPTPTLEMTSNEEEEMEMAVIYLQKLLRGRVVQNMMFEGKEKRLELIQELRTCHALQEDEKLVKKAEKQVTLALQRQRNLHEHKVSLVENHLAGLEGRALADMFDFLSKELVRLQEERRIHAFVMLAERQRRVREAEESGRRQVEKQRLREEDEIFKEVVKVHHSTISSYLEDIILNTEANTAEEQARAEIEKMAEKINDIAYEMESRRTYLQSEEIVAELVYSFLIPEVQKYFVKEKVRNAQRKHILAAHQIIHSYTESMVQKKLTEGEQDEASNAAMLLEKETQNENNS |
| 分子量 | 116.4 KDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人C3orf15蛋白的**示例参考文献**（注：由于该蛋白研究较为冷门，以下内容为假设性举例，建议通过PubMed或专业数据库查询真实文献）：
1. **文献名称**：*Molecular cloning and functional characterization of human C3orf15 in cell proliferation*
**作者**：Zhang Y et al.
**摘要**：研究通过重组表达技术获得了人C3orf15蛋白，发现其能通过调控MAPK信号通路抑制肿瘤细胞增殖。
2. **文献名称**：*Structural analysis of recombinant human C3orf15 reveals a novel enzymatic activity*
**作者**：Smith JR et al.
**摘要**：解析了重组C3orf15的晶体结构，发现其具有水解酶活性，可能参与脂质代谢。
3. **文献名称**：*C3orf15 knockout mice exhibit mitochondrial dysfunction and metabolic abnormalities*
**作者**：Tanaka K et al.
**摘要**：利用重组蛋白抗体检测C3orf15的组织分布，发现其缺失导致线粒体呼吸链功能受损。
4. **文献名称**：*Proteomic screening identifies C3orf15 as a biomarker in neurodegenerative diseases*
**作者**：Wang L et al.
**摘要**：通过质谱分析发现重组C3orf15在阿尔茨海默病模型中表达上调，提示其与神经退行性病变相关。
**建议**：实际研究中，推荐使用基因别名（如有）或访问UniProt（ID: Q8N3R3）获取最新信息，并结合文献库检索。
**Background of Recombinant Human C3orf15 Protein**
The human *C3orf15* gene (Chromosome 3 Open Reading Frame 15), also termed *FAM219A* or *C3ORF15*, encodes a protein with largely uncharacterized functions. Predominantly expressed in tissues like the pancreas, liver, and skeletal muscle, it is hypothesized to play roles in metabolic regulation and extracellular matrix interaction due to its structural features. Bioinformatics analyses suggest it contains a signal peptide and potential glycosylation sites, indicating secretion or membrane association.
Recombinant C3orf15 protein is produced using expression systems (e.g., *E. coli* or mammalian cells) to study its biochemical properties and interactions. Limited studies propose links to insulin signaling, lipid metabolism, and cancer progression, though mechanistic insights remain scarce. Its elevated expression in certain tumors hints at oncogenic potential, while its metabolic ties suggest relevance to diabetes or obesity. However, functional redundancy, lack of clear homologs in model organisms, and undefined pathways hinder research progress. Current efforts focus on structural characterization, ligand identification, and cell-based assays to clarify its physiological and pathological roles. The protein’s enigmatic nature underscores its potential as a novel biomarker or therapeutic target, warranting further exploration.
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