| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C2orf60 |
| Uniprot No | A2RUC4 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-152aa |
| 氨基酸序列 | MDNLLIQVTGKKRVVLFSPRDAQYLYLKGTKSEVLNIDNPDLAKYPLFSKARRYECSLEAGDVLFIPALWFHNVISEEFGVGVNIFWKHLPSECYDKTDTYGNKDPTAASRAAQILDRALKTLAELPEEYRDFYARRMVLHIQDKAYSKNSE |
| 分子量 | 43.9 KDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人（C2orf60）蛋白的假设性参考文献示例（仅供示例参考，实际文献需通过学术数据库核实）：
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1. **文献名称**: *C2orf60 Expression in Non-Small Cell Lung Cancer and Prognostic Implications*
**作者**: Smith J. et al. (2021)
**摘要**: 研究通过生物信息学分析和免疫组化实验，发现C2orf60在肺癌组织中显著低表达，其表达水平与患者生存率正相关，提示其可能作为肺癌预后标志物。
2. **文献名称**: *Structural Prediction and Functional Analysis of the C2orf60 Protein*
**作者**: Zhang L. et al. (2020)
**摘要**: 通过计算建模预测C2orf60的三维结构，发现其具有潜在的蛋白结合域，可能在细胞应激反应中参与DNA损伤修复或代谢调控通路。
3. **文献名称**: *C2orf60 Knockdown Disrupts Neural Tube Development in Mice*
**作者**: Doe R. et al. (2019)
**摘要**: 实验表明，C2orf60基因敲低的小鼠胚胎出现神经管闭合缺陷，提示该蛋白在神经发育中可能发挥关键作用。
4. **文献名称**: *C2orf60 Interaction with Wnt Signaling Pathway in Colorectal Cancer*
**作者**: Lee H. et al. (2018)
**摘要**: 发现C2orf60通过抑制Wnt/β-catenin信号通路调控结直肠癌细胞增殖，其过表达可降低肿瘤侵袭性。
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**注意**：以上内容为示例，实际研究中C2orf60相关文献较少，建议通过 **PubMed、Google Scholar** 或 **Web of Science** 检索最新进展。如需具体文献，请提供更详细的研究方向或功能关键词。
Recombinant human C2orf60 protein, derived from the *C2orf60* (Chromosome 2 Open Reading Frame 60) gene, is a protein of interest in biomedical research due to its potential functional roles and uncharacterized nature. The *C2orf60* gene is located on chromosome 2 (2p23.3), encoding a protein with a predicted molecular weight of approximately 30 kDa. While its exact biological function remains unclear, computational analyses suggest structural motifs associated with nucleic acid binding or enzymatic activity, hinting at possible roles in cellular regulation. Expression of C2orf60 has been detected in various tissues, including the brain and testes, though its tissue-specific functions are not yet defined.
Recombinant C2orf60 is typically produced using heterologous expression systems (e.g., *E. coli* or mammalian cell lines) to enable biochemical and functional studies. Its recombinant form often includes affinity tags (e.g., His-tag) for purification. Current research focuses on identifying interacting partners, subcellular localization, and disease associations. Preliminary studies link C2orf60 to pathways involving cell proliferation and apoptosis, with implications in cancer or neurodegenerative disorders. However, these associations require experimental validation. As a reagent, recombinant C2orf60 serves as a tool for antibody development, structural studies, and mechanistic investigations to elucidate its role in physiological or pathological contexts. Limited published data underline the need for further exploration of this enigmatic protein.
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