| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C20orf35 |
| Uniprot No | Q9BQY9 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-156aa |
| 氨基酸序列 | MAGQFRSYVWDPLLILSQIVLMQTVYYGSLGLWLALVDGLVRSSPSLDQMFDAEILGFSTPPGRLSMMSFILNALTCALGLLYFIRRGKQCLDFTVTVHFFHLLGCWFYSSRFPSALTWWLVQAVCIALMAVIGEYLCMRTELKEIPLNSAPKSNV |
| 分子量 | 44 KDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是3篇与重组人C20orf35蛋白相关的文献概览（注：C20orf35的官方名称为MSTP9，以下文献为虚拟示例供参考）：
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1. **文献名称**: *Functional characterization of recombinant human MSTP9/C20orf35 protein in cell proliferation*
**作者**: Li X, et al.
**摘要**: 研究通过大肠杆菌表达重组人MSTP9蛋白，发现其具有磷酸酶活性，并证明其过表达可抑制HeLa细胞增殖，提示其在细胞周期调控中的作用。
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2. **文献名称**: *Structural insights into the catalytic mechanism of human MSTP9*
**作者**: Zhang Y, et al.
**摘要**: 利用X射线晶体学解析重组MSTP9蛋白的三维结构，揭示其活性位点特征，并通过突变实验证实关键氨基酸残基对酶活性的影响，为靶向药物设计提供依据。
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3. **文献名称**: *MSTP9/C20orf35 interacts with p53 and modulates DNA damage response*
**作者**: Chen J, et al.
**摘要**: 该研究在HEK293细胞中表达重组MSTP9蛋白，通过免疫共沉淀发现其与p53蛋白相互作用，可能参与DNA损伤修复通路，功能缺失导致基因组不稳定性增加。
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**注意**：以上内容为模拟生成，C20orf35（MSTP9）的实际研究可能较少，建议通过PubMed或Google Scholar以官方名称检索最新文献。如需真实文献，可提供具体研究方向以便进一步筛选。
**Background of Recombinant Human C20orf35 Protein**
The C20orf35 (Chromosome 20 Open Reading Frame 35) gene, also designated as NIFK-antisense or TMEM230, encodes a poorly characterized protein conserved across vertebrates. Located on human chromosome 20q13.33, its gene structure suggests potential roles in cellular processes, though functional studies remain limited. The protein is predicted to contain transmembrane domains, implying possible localization to membranes or organelles, but experimental validation is sparse.
Interest in C20orf35 arises partly from its antisense overlap with the NIFK gene, hinting at regulatory interactions. Additionally, rare coding variants in TMEM230 (C20orf35) have been linked to Parkinson’s disease in small-scale studies, though this association remains controversial and under investigation. Recombinant C20orf35 protein is typically produced in bacterial or mammalian expression systems for biochemical studies, enabling exploration of its structure, interactors, and post-translational modifications. Emerging evidence suggests potential involvement in vesicle trafficking or RNA metabolism, but mechanistic insights are lacking. Current research focuses on clarifying its physiological roles, disease relevance, and utility as a biomarker or therapeutic target. The protein’s enigmatic nature underscores the need for further functional genomics and proteomics investigations.
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