| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C20orf26 |
| Uniprot No | Q8NHU2 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-200aa |
| 氨基酸序列 | MSYALSHTNRKLTLEPKITVNAKIIVVGASSVGISFLETLVFCSHMKFNNLTLISTHGLPGKKLLDTEQRKFLASDHCFNDKDYALMSLCSWVNVVVGRMTGIDRAAKHVVLSTDEIVPYDHLILCTGQQYQVPCPTEADISQHLTNREVPNSSQRRYTGKVPCNHFTLNEEEDCFKALIWIRNNSITTEDGGRASVLFC |
| 分子量 | 48.8 KDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是根据现有知识模拟的关于重组人C20orf26蛋白的参考文献示例（注：实际文献可能需要通过PubMed、Google Scholar等平台验证）：
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1. **"Structural characterization of C20orf26 reveals a novel protein fold"**
*Authors: Smith A.B., et al.*
摘要：本研究通过X射线晶体学解析了C20orf26蛋白的三维结构，发现其具有独特的折叠模式，暗示其可能作为分子伴侣或参与蛋白互作网络。
2. **"C20orf26 modulates cell cycle progression via interaction with mitotic kinases"**
*Authors: Lee C., et al.*
摘要：研究利用CRISPR敲除技术，发现C20orf26通过与Aurora激酶家族成员相互作用影响有丝分裂进程，提示其在细胞周期调控中的潜在功能。
3. **"C20orf26 expression is downregulated in glioblastoma and correlates with patient survival"**
*Authors: Garcia-Rico E., et al.*
摘要：通过分析癌症基因组图谱（TCGA）数据，发现C20orf26在胶质母细胞瘤中表达显著降低，其低表达与患者预后不良相关，可能作为肿瘤抑制因子。
4. **"Proteomic profiling identifies C20orf26 as a component of the mitochondrial ribosome assembly complex"**
*Authors: Zhang Y., et al.*
摘要：结合质谱分析技术，研究表明C20orf26定位于线粒体，可能参与核糖体组装过程的调控，为线粒体功能研究提供新靶点。
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**注意**：以上文献为模拟生成，实际研究可能有限或主题不完全匹配。建议通过学术数据库检索关键词（如“C20orf26 protein function”“C20orf26 gene”）获取真实文献。
**Background of Recombinant Human C20orf26 Protein**
The human C20orf26 protein, encoded by the *C20orf26* gene (Chromosome 20 Open Reading Frame 26), is a poorly characterized protein with limited functional annotation in current scientific literature. Located on chromosome 20q13.12, the gene spans approximately 13.4 kb and encodes a protein of 211 amino acids. While its exact biological role remains unclear, conserved domain analyses suggest potential functional motifs, including regions with homology to protein-binding or enzymatic domains, though these require experimental validation.
C20orf26 appears to be broadly expressed in human tissues, with moderate mRNA levels reported in organs like the brain, kidney, and testis. Subcellular localization predictions indicate potential cytoplasmic or nuclear distribution, hinting at roles in intracellular signaling or regulation. Some studies link C20orf26 to cellular processes such as DNA repair, apoptosis, or ubiquitination pathways, but mechanistic insights are scarce. Notably, bioinformatics analyses associate it with protein interaction networks involving cancer-related proteins, suggesting a possible connection to tumorigenesis. However, direct evidence linking C20orf26 to specific diseases is currently lacking.
Recombinant forms of C20orf26 are often generated for structural studies or functional assays to clarify its molecular interactions. Despite its obscurity, the protein’s conserved nature across vertebrates implies evolutionary significance. Further research is needed to elucidate its physiological and pathophysiological roles, making C20orf26 a candidate for exploratory studies in proteomics and cellular biology.
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