| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C1orf94 |
| Uniprot No | Q6P1W5 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-408aa |
| 氨基酸序列 | MPVISSRQDCDSATSTVTDILCAAEVKSSKGTEDRGRILGDSNLQVSKLLSQFPLKSTETSKVPDNKNVLDKTRVTKDFLQDNLFSGPGPKEPTGLSPFLLLPPRPPPARPDKLPELPAQKRQLPVFAKICSKPKADPAVERHHLMEWSPGTKEPKKGQGSLFLSQWPQSQKDACGEEGCCDAVGTASLTLPPKKPTCPAEKNLLYEFLGATKNPSGQPRLRNKVEVDGPELKFNAPVTVADKNNPKYTGNVFTPHFPTAMTSATLNQPLWLNLNYPPPPVFTNHSTFLQYQGLYPQQAARMPYQQALHPQLGCYSQQVMPYNPQQMGQQIFRSSYTPLLSYIPFVQPNYPYPQRTPPKMSANPRDPPLMAGDGPQYLFPQGYGFGSTSGGPLMHSPYFSSSGNGINF |
| 分子量 | 71.3 KDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人C1orf94蛋白的3篇文献概览（基于虚拟数据整理，仅供参考）：
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1. **文献名称**：*C1orf94 suppresses tumorigenesis by modulating the AKT/mTOR pathway in gastric cancer*
**作者**：Zhang Y, et al.
**摘要**：本研究通过重组C1orf94蛋白体外实验，发现其过表达可抑制胃癌细胞增殖和迁移，并证实其通过调控AKT/mTOR信号通路发挥抑癌作用。
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2. **文献名称**：*Structural insights into the interaction of C1orf94 with DNA repair machinery*
**作者**：Chen L, et al.
**摘要**：利用重组C1orf94蛋白进行X射线晶体学分析，揭示了其与DNA修复蛋白BRCA1的相互作用界面，提示其在基因组稳定性维持中的潜在功能。
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3. **文献名称**：*C1orf94 deficiency promotes mitochondrial dysfunction in neurodegenerative models*
**作者**：Wang H, et al.
**摘要**：通过重组C1orf94蛋白补偿实验，发现该蛋白在神经细胞线粒体能量代谢中起关键作用，缺乏会导致活性氧积累并加速神经元退化。
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**说明**：C1orf94研究尚处早期阶段，以上内容为模拟方向，实际文献需通过PubMed、Web of Science等平台以“C1orf94”、“recombinant protein”等关键词检索确认。
**Background of Recombinant Human C1orf94 Protein**
The C1orf94 (Chromosome 1 Open Reading Frame 94) gene, located on human chromosome 1q25.3, encodes a protein whose biological functions remain under investigation. Initially identified through genomic sequencing, C1orf94 is evolutionarily conserved across vertebrates, suggesting critical yet not fully characterized roles. Studies indicate its involvement in cellular processes such as proliferation and differentiation, potentially through interactions with signaling pathways or cytoskeletal components. Notably, C1orf94 expression is detected in tissues like the testis, brain, and certain cancers, hinting at tissue-specific functions or oncogenic relevance.
Recombinant C1orf94 protein is artificially produced using expression systems (e.g., *E. coli* or mammalian cells*) to enable functional studies. This engineered protein retains native structural features, allowing researchers to explore its biochemical properties, interactions, and potential therapeutic applications. Recent work has linked C1orf94 to cancer progression, with elevated expression observed in malignancies like glioblastoma and prostate cancer, possibly influencing cell migration or survival pathways. Structural predictions suggest coiled-coil domains, which may mediate protein-protein interactions.
Despite progress, C1orf94's precise mechanisms and physiological roles remain enigmatic. Its recombinant form serves as a vital tool for elucidating molecular functions, developing diagnostic biomarkers, or targeting pathways in disease contexts. Further studies are needed to decode its contributions to normal biology and pathology.
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