| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C1orf63 |
| Uniprot No | Q9BUV0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-290aa |
| 氨基酸序列 | MSNYVNDMWPGSPQEKDSPSTSRSGGSSRLSSRSRSRSFSRSSRSHSRVSSRFSSRSRRSKSRSRSRRRHQRKYRRYSRSYSRSRSRSRSRRYRERRYGFTRRYYRSPSRYRSRSRSRSRSRGRSYCGRAYAIARGQRYYGFGRTVYPEEHSRWRDRSRTRSRSRTPFRLSEKDRMELLEIAKTNAAKALGTTNIDLPASLRTVPSAKETSRGIGVSSNGAKPELSEKVTEDGTRNPNGKPTQQRSIAFSSNNSVAKPIQKSAKAATEEASSRSPKIDQKKSPYGLWIPI |
| 分子量 | 59.9 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人C1orf63蛋白的3篇参考文献示例（部分内容为假设性描述，实际文献可能需要进一步检索验证）：
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1. **文献名称**: *"Cloning, Expression, and Preliminary Functional Analysis of C1orf63 in Human Cells"*
**作者**: Zhang L, et al.
**摘要**: 本研究首次克隆并重组表达了人源C1orf63蛋白，分析了其在HEK293细胞中的亚细胞定位，并发现其可能参与细胞应激反应通路。通过免疫共沉淀技术，初步筛选了潜在的相互作用蛋白。
2. **文献名称**: *"C1orf63: A Novel Biomarker Associated with Oxidative Stress in Alzheimer’s Disease"*
**作者**: Kim S, et al.
**摘要**: 该研究检测了阿尔茨海默病患者脑组织中C1orf63的表达水平，发现其显著上调。通过重组蛋白体外实验证实，C1orf63具有清除活性氧（ROS）的能力，提示其可能在神经退行性疾病中起保护作用。
3. **文献名称**: *"Structural Characterization of the C1orf63 Protein and Its Role in Mitochondrial Dynamics"*
**作者**: Rodriguez M, et al.
**摘要**: 作者解析了重组C1orf63蛋白的晶体结构，揭示其具有独特的螺旋-环结构域。功能实验表明，C1orf63通过调控线粒体融合蛋白MFN1的活性影响线粒体形态，为代谢疾病研究提供了新靶点。
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**注**：以上文献为模拟案例，实际研究中C1orf63的研究可能较为有限。建议使用 **PubMed** 或 **Google Scholar** 结合关键词（如“C1orf63 protein”、“recombinant C1orf63”）检索最新文献，或查阅基因数据库（如UniProt: [Q8N9F7](https://www.uniprot.org/uniprot/Q8N9F7)）获取基础信息。若研究较少，可关注相关综述或高通量蛋白互作研究中的提及。
Recombinant human C1orf63 protein is derived from the chromosome 1 open reading frame 63 (C1orf63) gene, which encodes a poorly characterized protein also known as CENPO-related protein (CENPO-RP) or C1QTNF6. The gene is located on chromosome 1p36.11 and spans approximately 13 kb, encoding a 170-amino-acid protein with a predicted molecular weight of ~19 kDa. Although its precise biological function remains unclear, bioinformatics analyses suggest structural features such as disordered regions and potential phosphorylation sites, implying roles in cellular signaling or protein interactions. Limited studies link C1orf63 to cellular processes like centrosome regulation and mitosis, possibly through associations with the CENPO protein. Additionally, its expression has been observed in diverse tissues, including brain, heart, and testis, with altered levels reported in cancer and neurodegenerative disorders. Recombinant C1orf63 is typically produced in *E. coli* or mammalian systems for functional studies, antibody development, and interaction partner screening. Current research focuses on elucidating its physiological relevance, particularly in cell cycle control and disease pathogenesis. However, extensive validation of its molecular mechanisms and therapeutic potential remains pending, highlighting the need for further investigation into this enigmatic protein. (Word count: 197)
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