关键信息
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基因名
NMUR2
- 应用
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别名
NMUR2; NMU2R; TGR1; Neuromedin-U receptor 2; NMU-R2; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9GZQ4
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表达区间
1-415 aa
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氨基酸序列
MSGMEKLQNASWIYQQKLEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVSVVYVPIFVVGVIGNVLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCYFKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLPNTSIHGIKFHYFPNGSLVPGSATFTVIKPMWIYNFIIQVTSFLFYLLPMTVISVLYYLMALRLKKDKSLEADEGNANIQRPCRKSVNKMLFVLVLVFAICWAPFHIDRLFFSFVEEWSESLAAVFNLVHVVSGVFFYLSSAVNPIIYNLLSRRFQAAFQNVISSFHKQWHSQHDPQLPPAQRNIFLTECHFVELTEDIGPQFPCQSSMHNSHLPTALSSEQMSRTNYQSFHFNKT
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分子量
71.39 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
NMUR2, or Neuromedin U Receptor 2, is a G protein-coupled receptor (GPCR) that plays a critical role in various physiological functions, including energy homeostasis, stress response, and neuroendocrine regulation. As an important player in the neuromedin U signaling pathway, NMUR2 is implicated in several metabolic disorders, obesity, and mood regulation, making it a potential therapeutic target for drug development. The research surrounding NMUR2 recombinant proteins focuses on elucidating its structure, function, and signaling mechanisms to better understand its role in health and disease. The generation of high-quality NMUR2 recombinant proteins facilitates biochemical and pharmacological studies, allowing researchers to investigate receptor-ligand interactions, cell signaling pathways, and potential drug candidates. Additionally, understanding the receptor's structural characteristics can provide insights into the design of selective agonists or antagonists, thereby advancing the development of novel therapeutic strategies for metabolic and psychiatric disorders. Overall, the study of NMUR2 recombinant proteins is crucial for paving the way toward innovative treatments, highlighting the significance of GPCRs in biomedical research.
