关键信息
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基因名
NKX2-8
- 应用
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别名
Homeobox protein NK 2 homolog H ; Homeobox protein NK-2 homolog H; Homeobox protein Nkx 2.8; Homeobox protein Nkx-2.8; NK 2 homolog 8; NK 2 homolog H; NK2 homeobox 8; NK2 transcription factor related; locus 8; Nkx2 9; Nkx2-8; NKX2.8; NKX28_HUMAN; NKX2G; NKX2H; OTTHUMP00000027959
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15522
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表达区间
1-239 aa
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氨基酸序列
MATSGRLSFT VRSLLDLPEQ DAQHLPRREP EPRAPQPDPC AAWLDSERGH YPSSDESSLE TSPPDSSQRP SARPASPGSD AEKRKKRRVL FSKAQTLELE RRFRQQRYLS APEREQLASL LRLTPTQVKI WFQNHRYKLK RARAPGAAES PDLAASAELH AAPGLLRRVV VPVLVRDGQP CGGGGGGEVG TAAAQEKCGA PPAAACPLPG YPAFGPGSAL GLFPAYQHLA SPALVSWNW
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分子量
25.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
NKX2-8 is a member of the NK2 homeobox gene family, primarily known for its role in regulating developmental processes in various tissues. This transcription factor is critically involved in the development and function of the thyroid gland, lungs, and neural tissues. Recent studies have indicated that NKX2-8 may have pivotal roles beyond development, including potential implications in cancer biology and regenerative medicine. The expression of NKX2-8 has been observed in several tumor types, suggesting a possible involvement in tumorigenesis, making it a relevant target for therapeutic interventions. Furthermore, understanding the molecular mechanisms by which NKX2-8 operates can provide insights into its role in maintaining cellular homeostasis and tissue-specific functions. The development of recombinant NKX2-8 protein has facilitated these investigations, allowing researchers to explore its functional properties, interactions with other proteins, and impacts on cellular pathways. This research is crucial for unraveling the complexities of NKX2-8 in health and disease, with the potential to unlock new strategies for treatment and management of related disorders.
