关键信息
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基因名
MRPS14
- 应用
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别名
MRPS14; 28S ribosomal protein S14; mitochondrial; MRP-S14; S14mt; Mitochondrial small ribosomal subunit protein uS14m
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O60783
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表达区间
1-128 aa
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氨基酸序列
MAAFMLGSLL RTFKQMVPSS ASGQVRSHYV DWRMWRDVKR RKMAYEYADE RLRINSLRKN TILPKILQDV ADEEIAALPR DSCPVRIRNR CVMTSRPRGV KRRWRLSRIV FRHLADHGQL SGIQRATW
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分子量
15.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MRPS14, also known as mitochondrial ribosomal protein S14, is a crucial component of the mitochondrial ribosome, which plays a significant role in the translation of mitochondrial DNA-encoded proteins essential for oxidative phosphorylation. Research on MRPS14 has gained importance due to its involvement in mitochondrial function, cellular energy metabolism, and potential links to various diseases, including neurodegenerative disorders and certain types of cancer. Variants of MRPS14 have been implicated in mitochondrial dysfunction, which can lead to impaired ATP production and increased oxidative stress. Understanding the structure and function of MRPS14 can provide insights into the molecular mechanisms underlying mitochondrial-related diseases and may offer potential therapeutic targets. The study of MRPS14, particularly through recombinant protein techniques, allows for the examination of its biochemical properties and interactions within the mitochondrial ribosome, advancing our knowledge of mitochondrial biology and highlighting its significance in health and disease.
