关键信息
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基因名
MRGX2
- 应用
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别名
MRGPRX2; MRGX2; Mas-related G-protein coupled receptor member X2
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96LB1
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表达区间
1-330 aa
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氨基酸序列
MDPTTPAWGTESTTVNGNDQAPLLLCGKETLIPVFLILFIALVGLVGNGFVLWLLGFRMRRNAFSVYVLSLAGADFLFLCFQIINCLVYLSNFFCSISINFPSFFTTVMTCAYLAGLSMLSTVSTERCLSVLWPIWYRCRRPRHLSAVVCVLLWALSLLLSILEGKFCGFLFSDGDSGWCQTFDFITAAWLIFLFMVLCGSSLALLVRILCGSRGLPLTRLYLTILLTVLVFLLCGLPFGIQWFLILWIWKDSDVLFCHIHPVSVVLSSLNSSANPIIYFFVGSFRKQWRLQQPILKLALQRALQDIAEVDHSEGCFRQGTPEMSRSSLV
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分子量
62.04 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MRGX2, also known as Mas-related G protein-coupled receptor X2, is a member of the Mas-related gene (MRG) family, which plays a crucial role in nociception and inflammatory responses. Initially discovered for its involvement in pain signaling, MRGX2 has attracted significant research interest due to its unique expression patterns in sensory neurons and its potential implications in various pain conditions. Recent studies have suggested that MRGX2 may function as a modulator of nociceptive pathways, influencing both acute and chronic pain responses. Moreover, its interaction with endogenous peptides and ligands highlights its role in mediating inflammatory pain and possibly in the development of itch. Given its specific expression in pain-related pathways and the complexity of its signaling mechanisms, MRGX2 is considered a promising target for novel analgesic therapies. The recombinant expression of MRGX2 protein allows researchers to investigate its functional properties, binding affinities, and downstream signaling pathways in detail, providing insights into its biological roles and therapeutic potential. This research could lead to the development of innovative strategies for managing pain and inflammation, marking a significant advancement in pain management and enhancing our understanding of pain biology.
