关键信息
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基因名
MDFI
- 应用
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别名
MDFI; MyoD family inhibitor; Myogenic repressor I-mf
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q99750
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表达区间
1-246aa
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氨基酸序列
MYQVSGQRPS GCDAPYGAPS AAPGPAQTLS LLPGLEVVTG STHPAEAAPE EGSLEEAATP MPQGNGPGIP QGLDSTDLDV PTEAVTCQPQ GNPLGCTPLL PNDSGHPSEL GGTRRAGNGA LGGPKAHRKL QTHPSLASQG SKKSKSSSKS TTSQIPLQAQ EDCCVHCILS CLFCEFLTLC NIVLDCATCG SCSSEDSCLC CCCCGSGECA DCDLPCDLDC GILDACCESA DCLEICMECC GLCFSS
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分子量
25 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MDFI, or Myeloid Differentiation Factor 1, is a critical protein involved in various cellular processes, including myeloid differentiation, immune response modulation, and apoptosis. Research into MDFI has gained momentum due to its potential implications in cancer biology and autoimmune diseases. Notably, its expression patterns and functions suggest a role in the development and progression of certain malignancies, as well as in the regulation of inflammatory responses. Scientists have been particularly interested in understanding how MDFI interacts with other cellular pathways and proteins, which could reveal novel therapeutic targets. Recent studies have demonstrated that modulating MDFI levels can influence cellular functions, making it a promising candidate for drug development in treating hematological malignancies and autoimmune disorders. Moreover, understanding the structural biology of MDFI through techniques such as X-ray crystallography and cryo-electron microscopy could provide insights into its functional mechanisms. As such, ongoing research aims to elucidate the precise biological roles of MDFI, its molecular interactions, and its potential as a biomarker, thereby advancing our knowledge in both basic and clinical sciences related to immunology and oncology.
