关键信息
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基因名
MREG
- 应用
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别名
MREG;DSU;Melanoregulin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N565
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表达区间
1-214aa
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氨基酸序列
MGLRDWLRTV CCCCGCECLE ERALPEKEPL VSDNNPYSSF GATLVRDDEK NLWSMPHDVS HTEADDDRTL YNLIVIRNQQ AKDSEEWQKL NYDIHTLRQV RREVRNRWKC ILEDLGFQKE ADSLLSVTKL STISDSKNTR KAREMLLKLA EETNIFPTSW ELSERYLFVV DRLIALDAAE EFFKLARRTY PKKPGVPCLA DGQKELHYLP FPSP
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MREG, or Migration Regulator Protein, plays a critical role in cellular processes, particularly in cellular migration and the development of various tissues. Recent studies have highlighted its involvement in regulating endothelial cell function and angiogenesis, crucial for wound healing and tissue regeneration. Aberrant expression or dysfunction of MREG has been linked to several pathological conditions, including cancer metastasis and cardiovascular diseases, underscoring its potential as a therapeutic target. The recombinant MREG protein has become a focal point for research aimed at understanding its precise mechanisms of action and interactions within signaling pathways. By producing MREG as a recombinant protein, researchers can investigate its structure-function relationships, post-translational modifications, and effects on cell behavior in various experimental contexts. This foundational knowledge is essential for developing strategies to manipulate MREG activity in clinical applications, such as enhancing tissue repair or inhibiting tumor progression. As such, MREG represents an exciting frontier in biomedical research with implications for both understanding fundamental biological processes and developing novel therapeutic approaches.
