Cat: PA2000-4377

Recombinant Human Pf4 Protein,His

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关键信息

  • 基因名

    Pf4

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Pf4;CXCL4V1;SCYB4V1;Platelet factor 4 variant

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P02776

  • 表达区间

    31-101aa

  • 氨基酸序列

    EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES

  • 分子量

    8 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

质检流程

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背景信息

Pf4 recombinant protein, derived from the Plasmodium falciparum 4 (Pf4) gene, has garnered significant attention in malaria research due to its potential implications in vaccine development and therapeutic strategies. Plasmodium falciparum, the deadliest malaria-causing parasite, continues to pose a major global health challenge, particularly in tropical regions. Traditional control measures, such as insecticide-treated bed nets and antimalarial drugs, have faced growing resistance, necessitating the exploration of innovative approaches. The Pf4 protein, believed to play a crucial role in the parasite's invasion of red blood cells and its survival within the human host, has emerged as a promising target for intervention. Recent studies have focused on the characterization of Pf4 recombinant proteins to better understand their immunogenic properties and potential to elicit protective immune responses. By producing Pf4 in a recombinant form, researchers aim to evaluate its efficacy as a vaccine component, potentially leading to the development of new immunization strategies that could complement existing malaria control measures. The ongoing investigation into Pf4 recombinant protein not only seeks to unveil its biological function but also endeavors to leverage its properties to enhance vaccine formulations and therapeutic designs, ultimately contributing to the global efforts aimed at malaria eradication.

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