关键信息
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基因名
SLC27A5
- 应用
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别名
SLC27A5；ACSB；ACSVL6；FACVL3；Long-chain fatty acid transport Protein 5
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y2P5
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表达区间
1-690aa
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氨基酸序列
MGVRQQLALLLLLLLLLWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAM LARPWLGPWVPHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHL GLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELDA RACQAAWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCP TAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCF YLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTG LPKPAILTHERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCL DLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRT HTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCGA LGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVV SQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDR LGDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQ LAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRLVR EGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWRL
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分子量
75.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
SLC27A5, also known as fatty acid transport protein 5 (FATP5), is a member of the SLC27 family of solute carrier proteins that plays a critical role in the cellular uptake of long-chain fatty acids (LCFAs). The importance of SLC27A5 has garnered attention due to its implications in various physiological processes, including lipid metabolism, energy homeostasis, and the regulation of inflammatory responses. Abnormal expression or mutations in SLC27A5 have been linked to metabolic disorders, obesity, and conditions such as non-alcoholic fatty liver disease (NAFLD). Recent studies have focused on the production of recombinant SLC27A5 proteins to elucidate its functional mechanisms and to explore potential therapeutic applications. Recombinant protein studies facilitate the examination of the structure-function relationship of SLC27A5 and its interaction with fatty acids, thereby enhancing our understanding of its role in human health and disease. Additionally, the development of SLC27A5 inhibitors or activators may provide novel strategies for managing metabolic disorders and associated complications. This research direction underscores the necessity for a deeper understanding of SLC27A5's mechanistic pathways and its potential as a drug target in metabolic diseases, paving the way for future advancements in clinical treatments.
