| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Solute carrier family 22 member 4, Ergothioneine transporter, ET transporter, Organic cation/carnitine transporter 1, SLC22A4, ETT, OCTN1, UT2H |
| Entrez GeneID | 6583 |
| WB Predicted band size | 62.2kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This SLC22A4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 514-542 amino acids from the C-terminal region of human SLC22A4. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于SLC22A4抗体的3篇代表性文献摘要信息:
1. **文献名称**:The role of SLC22A4 in inflammatory bowel disease: Insights from antibody-based expression analysis
**作者**:Tokuhira et al.
**摘要**:通过免疫组化和Western blot分析,发现SLC22A4蛋白在肠道上皮细胞中高表达,其抗体检测显示IBD患者中表达异常,提示其可能参与肠道炎症调节。
2. **文献名称**:Functional characterization of SLC22A4 variants using a monoclonal antibody approach
**作者**:Urban et al.
**摘要**:开发针对SLC22A4的单克隆抗体,验证其特异性后用于细胞膜定位研究,发现特定SNP(rs1050152)影响蛋白转运功能,与类风湿性关节炎风险相关。
3. **文献名称**:SLC22A4 mediates carnitine transport in human cells: Antibody validation and functional assays
**作者**:Tamai et al.
**摘要**:通过抗体阻断实验证实SLC22A4在肉碱转运中的关键作用,研究显示该抗体可抑制细胞对肉碱的摄取,为代谢疾病机制提供新证据。
*注:以上内容为模拟文献概括,实际引用需查询具体论文数据库(如PubMed)。建议以关键词"SLC22A4 antibody"+"expression/function/disease"检索近年高被引论文。*
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