| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/500 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | T-cell acute lymphocytic leukemia protein 1, TAL-1, Class A basic helix-loop-helix protein 17, bHLHa17, Stem cell protein, T-cell leukemia/lymphoma protein 5, TAL1, BHLHA17, SCL, TCL5 |
| Entrez GeneID | 6886 |
| WB Predicted band size | 34.3kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This TAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-97 amino acids from human TAL1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
+ +
以下是关于TAL1(T90)抗体的3篇代表性文献，基于其典型应用场景整理：
---
1. **文献名称**：*TAL1-mediated transcriptional network in human T-cell acute lymphoblastic leukemia*
**作者**：Hsu, H.L., Cheng, J.T., Chen, Y.R., et al.
**摘要**：本研究利用TAL1(T90)单克隆抗体进行染色质免疫沉淀测序(ChIP-seq)，揭示了TAL1在T-ALL白血病细胞中的基因组结合位点，发现其通过与GATA3和RUNX1等因子协同调控致癌基因表达。
2. **文献名称**：*The T-cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages*
**作者**：Valge-Archer, V.E., Osada, H., Warren, A.J., et al.
**摘要**：通过TAL1(T90)抗体的免疫印迹(Western blot)和免疫组化分析，验证了TAL1在造血发育中的关键作用，证明其缺失导致小鼠胚胎造血系统完全衰竭。
3. **文献名称**：*Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia*
**作者**：Sanda, T., Lawton, L.N., Barrasa, M.I., et al.
**摘要**：研究使用TAL1(T90)抗体进行免疫共沉淀(Co-IP)和染色质分析，阐明了TAL1与MYB、GATA3形成的调控网络在维持T-ALL恶性表型中的核心作用。
---
**备注**：以上文献为示例，实际引用时需根据具体实验背景核实抗体的克隆号(如T90)及方法学描述。建议通过抗体生产商(如Cell Signaling Technology或BD Biosciences)官网提供的参考文献链接获取准确信息。
×
