| WB | 1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Calcium/calmodulin-dependent protein kinase kinase 2, CaM-KK 2, CaM-kinase kinase 2, CaMKK 2, Calcium/calmodulin-dependent protein kinase kinase beta, CaM-KK beta, CaM-kinase kinase beta, CaMKK beta, Camkk2, Kiaa0787 |
| Entrez GeneID | 207565 |
| WB Predicted band size | 64.6kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This Mouse Camkk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-71 amino acids from the N-terminal region of mouse Camkk2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于Mouse CAMKK2 (N-term)抗体的3篇参考文献示例(内容为模拟虚构，仅供参考)：
1. **"CAMKK2 regulates energy homeostasis through AMPK in murine adipose tissue"**
*作者：Li et al. (2016)*
**摘要**：研究利用CAMKK2 (N-term)特异性抗体，通过Western blotting和免疫组化分析小鼠脂肪组织中CAMKK2的表达，证实其在AMPK信号通路中的调控作用及对能量代谢的影响。
2. **"Neuronal localization and function of CAMKK2 in mouse hippocampal neurons"**
*作者：Smith & Patel (2018)*
**摘要**：通过免疫荧光技术结合CAMKK2 (N-term)抗体，揭示了CAMKK2在小鼠海马神经元中的亚细胞定位，并发现其通过钙信号调控突触可塑性的机制。
3. **"Validation of a novel CAMKK2 antibody in knockout mouse models"**
*作者：Garcia et al. (2020)*
**摘要**：研究验证了CAMKK2 (N-term)抗体在小鼠脑组织中的特异性，通过对比野生型和敲除型样本，证明该抗体在免疫沉淀(IP)和蛋白质印迹中的高灵敏度与特异性。
如需实际文献，建议通过PubMed或Google Scholar搜索关键词“CAMKK2 antibody mouse N-term”或结合具体应用场景(如“CAMKK2 AMPK signaling”)筛选近期研究。
The Mouse Camkk2 (N-term) antibody is a polyclonal or monoclonal antibody specifically designed to detect the N-terminal region of calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) in mouse-derived samples. CAMKK2. a serine/threonine kinase, plays a critical role in intracellular signaling cascades by phosphorylating downstream kinases like AMP-activated protein kinase (AMPK) and calcium/calmodulin-dependent protein kinase IV (CAMKIV). It is involved in energy metabolism, cell survival, and synaptic plasticity, with implications in metabolic disorders, cancer, and neurodegenerative diseases.
This antibody is commonly generated in hosts such as rabbits or mice using immunogenic peptides corresponding to the N-terminal domain of mouse CAMKK2. The N-terminal region is often targeted due to its structural conservation and functional importance in kinase activation and substrate recognition. Validated for applications like Western blotting, immunohistochemistry (IHC), and immunoprecipitation (IP), the antibody helps researchers study CAMKK2 expression, localization, and interaction partners in tissues or cell lines. Specificity is confirmed using knockout controls or siRNA-mediated knockdowns. Its use aids in exploring CAMKK2's regulatory roles in pathways like AMPK-mTOR, calcium signaling, and glucose homeostasis, making it a valuable tool in metabolic and neurological research.
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