| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/500 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Transient receptor potential cation channel subfamily V member 3, TrpV3, Trpv3 |
| Entrez GeneID | 246788 |
| WB Predicted band size | 90.7kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Mouse |
| Immunogen | This Mouse TRPV3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the N-terminal region of mouse TRPV3. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
+ +
以下是关于Mouse TRPV3 (N-term)抗体的3篇参考文献示例(文献信息为虚构示例，仅用于格式参考)：
1. **文献名称**：*Characterization of a Novel TRPV3 Antibody for Immunohistochemical Analysis in Mouse Tissues*
**作者**：Smith A, et al.
**摘要**：本研究开发并验证了一种针对小鼠TRPV3 N端表位的特异性抗体，通过Western blot和免疫组化证实其在皮肤和背根神经节中的表达，并验证其在TRPV3基因敲除小鼠中的特异性。
2. **文献名称**：*TRPV3 Channel Modulation by Lipids Revealed Through N-terminal Antibody Blockade*
**作者**：Chen L, et al.
**摘要**：利用小鼠TRPV3 N端抗体阻断通道功能，研究脂质分子对TRPV3活性的调控作用，揭示其N端结构域在通道门控中的关键作用。
3. **文献名称**：*Differential Expression of TRPV3 in Cutaneous Sensory Neurons Using a Novel N-term Specific Antibody*
**作者**：Wang X, et al.
**摘要**：通过新开发的TRPV3 N端抗体，发现TRPV3在小鼠皮肤感觉神经元中的差异性表达，并探讨其在热痛觉传导中的潜在机制。
(注：以上文献为示例，实际文献需通过PubMed或Google Scholar检索确认。)
The Mouse TRPV3 (N-term) antibody is a polyclonal or monoclonal antibody specifically designed to target the N-terminal region of the transient receptor potential vanilloid 3 (TRPV3) channel in mice. TRPV3. a member of the TRP ion channel family, is a calcium-permeable, non-selective cation channel primarily expressed in epithelial cells, keratinocytes, and sensory neurons. It plays critical roles in thermosensation, skin barrier function, hair growth, and inflammatory responses. The N-terminal domain of TRPV3 is essential for channel assembly, ligand binding, and modulation by temperature or chemical agonists (e.g., camphor, carvacrol).
This antibody is typically generated by immunizing hosts (e.g., rabbits, mice) with a synthetic peptide or recombinant protein corresponding to the N-terminal sequence of mouse TRPV3. It is validated for applications such as Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and immunoprecipitation (IP) to detect endogenous TRPV3 expression in tissues or cell lines. Specificity is confirmed using TRPV3 knockout controls or blocking peptides. Researchers employ this tool to study TRPV3's involvement in skin disorders (e.g., dermatitis, pruritus), pain signaling, and temperature-sensitive pathways. Its reliability in distinguishing TRPV3 from homologous TRP channels (e.g., TRPV1. TRPV4) underscores its utility in mechanistic studies of sensory biology and disease models.
×
