WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/100-1/500 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Fatty acid desaturase 6, 11419-, FADS6 |
Entrez GeneID | 283985 |
WB Predicted band size | 40.4kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | This FADS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-332 amino acids from the C-terminal region of human FADS6. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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关于FADS6抗体的研究目前非常有限,可能存在基因符号拼写或编号错误(如FADS家族常见基因为FADS1、FADS2等)。以下为基于假设的模拟文献示例,仅供参考:
1. **"Characterization of FADS6 Antibody in Lipid Metabolism Studies"**
*Smith A, et al. (2022)*
摘要:研究开发了一种特异性抗FADS6的多克隆抗体,用于检测该酶在肝组织中的表达,并探讨其与ω-3脂肪酸代谢的潜在关联。
2. **"FADS6 Expression in Cancer: An Immunohistochemical Analysis"**
*Lee B, et al. (2021)*
摘要:利用抗FADS6抗体进行免疫组化实验,发现其在乳腺癌细胞中异常高表达,提示可能与肿瘤脂质合成通路相关。
3. **"Validation of a Commercial FADS6 Antibody for Western Blot Applications"**
*Garcia C, et al. (2020)*
摘要:评估了某品牌FADS6抗体的特异性,发现其在人脑组织裂解液中可识别约45 kDa的蛋白条带,但需注意与其他FADS家族蛋白的潜在交叉反应。
**注意**:以上内容为模拟生成,FADS6可能并非标准基因名称,建议核实基因符号或查阅最新数据库(如NCBI Gene或UniProt)。
The FADS6 antibody is a research tool designed to target and detect the Fatty Acid Desaturase 6 (FADS6) protein, a member of the fatty acid desaturase (FADS) enzyme family. These enzymes catalyze the introduction of double bonds into fatty acid chains, influencing the biosynthesis of polyunsaturated fatty acids (PUFAs) like omega-3 and omega-6. which are critical for cellular membrane integrity, inflammation regulation, and neurological function. While FADS1. FADS2. and FADS3 are well-characterized, FADS6 remains less studied, with its specific role and substrate specificity still under investigation.
FADS6 antibodies are typically developed using immunogenic peptide sequences derived from conserved regions of the protein. They are employed in techniques such as Western blotting, immunohistochemistry, and ELISA to analyze FADS6 expression patterns, localization, and regulation in tissues or cell lines. Research involving FADS6 antibodies aims to clarify its potential involvement in lipid metabolism disorders, cancer progression, or metabolic syndromes.
Despite its emerging significance, the biological relevance of FADS6 and its antibody applications require further validation. Cross-reactivity with other FADS isoforms remains a concern, emphasizing the need for rigorous specificity testing. Current studies leverage FADS6 antibodies to explore its interactions with lipid pathways, offering insights into therapeutic targets for diseases linked to PUFA imbalances.
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