| WB | 1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Putative T-complex protein 1 subunit theta-like 2, CCT8L2, CESK1 |
| Entrez GeneID | 150160 |
| WB Predicted band size | 59.4kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This CCT8L2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 511-542 amino acids from human CCT8L2. |
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以下是模拟生成的关于CCT8L2抗体的参考文献(实际文献需通过数据库验证)：
1. **文献名称**：*CCT8L2 Expression in Human Testicular Tissues and Its Role in Spermatogenesis*
**作者**：Smith A, et al.
**摘要**：研究利用CCT8L2抗体通过免疫组化技术，揭示其在人类睾丸组织中的特异性表达模式，表明CCT8L2可能参与精子发生的分子调控，尤其在减数分裂阶段发挥作用。
2. **文献名称**：*Characterization of CCT8L2 Antibody for Detection of Chaperonin Complex Variants in Cancer Cells*
**作者**：Li X, et al.
**摘要**：验证了CCT8L2抗体的特异性，并发现其在多种癌细胞系中高表达，提示CCT8L2可能与肿瘤细胞增殖及应激反应中的蛋白质折叠功能相关。
3. **文献名称**：*A Novel Role of CCT8L2 in Neurodegenerative Diseases: Insights from Antibody-Based Proteomic Analysis*
**作者**：Park J, et al.
**摘要**：通过Western blot和免疫荧光技术，发现CCT8L2在阿尔茨海默病患者脑组织中的异常聚集，暗示其错误折叠可能参与神经退行性病变的病理机制。
4. **文献名称**：*CCT8L2 Antibody Development and Application in High-Throughput Screening Assays*
**作者**：Garcia R, et al.
**摘要**：报道了一种新型CCT8L2单克隆抗体的开发流程，并应用于高通量药物筛选平台，以识别调控CCT8L2功能的潜在化合物。
**注意**：以上文献为示例，实际引用需查询PubMed、Google Scholar等数据库确认存在性及准确性。
The CCT8L2 antibody is a research tool designed to target the CCT8-like protein 2 (CCT8L2), a subunit of the chaperonin-containing TCP1 (CCT) complex, also known as TRiC. The CCT complex plays a critical role in protein folding, assisting in the proper assembly of cytoskeletal proteins like actin and tubulin, as well as other cellular components. While CCT8 is a well-characterized subunit of this complex, CCT8L2 is a less-studied paralog with potential functional redundancy or specialized roles. Its exact biological significance remains under investigation, though studies suggest possible links to cellular stress responses and disease pathways.
The CCT8L2 antibody is typically developed in model organisms (e.g., rabbit or mouse) and validated for applications such as Western blotting, immunofluorescence, or immunoprecipitation. It enables researchers to study the expression, localization, and interactions of CCT8L2 in various tissues or disease models. Due to the structural similarity between CCT8 and CCT8L2. antibody specificity is a key focus, requiring rigorous validation to avoid cross-reactivity. Emerging research explores its relevance in cancer, neurodegeneration, and developmental disorders, positioning CCT8L2 as a potential biomarker or therapeutic target. However, further functional studies are needed to clarify its role in health and disease.
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