关键信息
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基因名
FABP1
- 应用
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别名
FABP1；FABPL;Fatty acid-binding Protein. liver
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P07148
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表达区间
1-127aa
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氨基酸序列
MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGDIITNTMTLGDIVFKRISKRI
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分子量
16.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Fatty Acid Binding Protein 1 (FABP1), a member of the FABP family, plays a critical role in the intracellular transport and metabolism of fatty acids, influencing various physiological processes, including lipid metabolism and insulin sensitivity. Studies have shown that FABP1 is primarily expressed in the liver and is involved in the regulation of lipid homeostasis and inflammation. Its significance extends beyond basic metabolism, as altered FABP1 expression is associated with metabolic disorders, such as obesity and type 2 diabetes. Researchers are increasingly interested in recombinant FABP1 proteins for their potential applications in drug development and therapeutic strategies, as well as their utility in unraveling the intricate molecular mechanisms underlying fat metabolism. Recombinant production of FABP1 has made it possible to explore its structure-function relationships, enabling detailed studies on how FABP1 interacts with fatty acids and other cellular targets. Understanding these interactions may lead to the identification of novel biomarkers for metabolic diseases and facilitate the design of targeted therapies aimed at combating disorders linked to dysregulated lipid metabolism. Furthermore, FABP1's role in cellular signaling pathways highlights its potential as a therapeutic target, making recombinant FABP1 an important focus of current biomedical research aimed at addressing global health issues related to obesity and metabolic syndrome. As such, the elucidation of FABP1's functions through recombinant protein studies represents a promising frontier in the quest to develop innovative interventions for metabolic diseases.
