| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Olfactory receptor 1F1, Olfactory receptor 16-35, OR16-35, Olfactory receptor 1F10, Olfactory receptor 1F4, Olfactory receptor 1F5, Olfactory receptor 1F6, Olfactory receptor 1F7, Olfactory receptor 1F8, Olfactory receptor 1F9, Olfactory receptor OR16-4, OR1F1 |
| Entrez GeneID | 4992 |
| WB Predicted band size | 34.9kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This OR1F1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-303 amino acids from the C-terminal region of human OR1F1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
+ +
以下是关于OR1F1 (C-term)抗体的3篇参考文献示例，内容基于学术研究场景的合理推测：
---
1. **文献名称**：*"Characterization of Olfactory Receptor OR1F1 Expression in Human Tissues"*
**作者**：Smith A. et al.
**摘要**：本研究利用针对OR1F1 C端结构域的特异性抗体，通过免疫组化技术揭示了该受体在嗅觉上皮和非嗅觉组织(如睾丸和肺)中的分布，证实了其多组织表达模式。
2. **文献名称**：*"Antibody Validation for GPCRs: A Case Study on Olfactory Receptors"*
**作者**：Lee J. & Müller C.
**摘要**：文章系统评估了多种GPCR抗体的特异性，包括OR1F1 (C-term)抗体。通过敲除细胞系验证，证明该抗体在Western blot和免疫荧光中具有高特异性，但存在组织交叉反应性风险。
3. **文献名称**：*"Functional Analysis of OR1F1 in Odorant Signal Transduction"*
**作者**：Zhang Y. et al.
**摘要**：研究利用OR1F1 C端抗体进行共免疫沉淀实验，发现其与下游G蛋白的相互作用，揭示了该受体在嗅觉信号转导中的关键结构域作用。
---
**注意**：上述文献为模拟示例，实际文献需通过PubMed、Google Scholar等平台检索。若研究较少，可扩展关键词(如“OR1F1 antibody validation”)或查阅抗体供应商(如Santa Cruz、Abcam)提供的技术文档及引用论文。
The OR1F1 (C-term) antibody is a specialized tool designed to target the C-terminal region of the olfactory receptor 1F1 (OR1F1), a member of the olfactory receptor (OR) family. Olfactory receptors are G protein-coupled receptors (GPCRs) predominantly expressed in olfactory sensory neurons, where they play a critical role in detecting odorants and mediating the sense of smell. OR1F1. like other ORs, is characterized by a seven-transmembrane domain structure, with the C-terminal region located intracellularly. This region is often involved in receptor trafficking, signal transduction, or interactions with downstream signaling components, making it a focal point for studying receptor function and regulation.
The OR1F1 (C-term) antibody is commonly utilized in research to investigate the expression, localization, and biochemical properties of OR1F1 in various biological samples, such as tissues or cell lines. It enables techniques like Western blotting, immunohistochemistry, or immunofluorescence to detect the receptor's presence and distribution. Given the tissue-specific and often low expression levels of olfactory receptors, this antibody aids in exploring their roles beyond olfaction, including potential functions in non-sensory tissues or disease contexts. Studies involving OR1F1 may also contribute to understanding broader GPCR signaling mechanisms or developing therapeutic targets for disorders linked to olfactory dysfunction. Validation of antibody specificity through controls (e.g., knockout models) is essential to ensure reliable results.
×
