| WB | 1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/25 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Putative T-complex protein 1 subunit theta-like 2, CCT8L2, CESK1 |
| Entrez GeneID | 150160 |
| WB Predicted band size | 59.4kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This CCT8L2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 92-124 amino acids from human CCT8L2. |
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以下是关于CCT8L2 (N-Term)抗体的示例参考文献(注：由于该靶点研究可能较新或较少，以下文献为假设性示例，供参考格式)：
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1. **文献名称**: *Characterization of CCT8L2 Antibody Specificity in Mammalian Protein Folding Studies*
**作者**: Zhang L, et al.
**摘要**: 本研究验证了CCT8L2 (N-Term)抗体在识别人类和小鼠组织中的CCT8L2蛋白N末端结构域的特异性。通过免疫印迹和免疫组化实验，证实该抗体在检测CCT8L2在细胞应激条件下的表达变化中的应用价值。
2. **文献名称**: *CCT8L2 Interaction Networks Revealed by Immunoprecipitation Using N-Terminal Antibodies*
**作者**: Gupta S, et al.
**摘要**: 利用CCT8L2 (N-Term)抗体进行免疫共沉淀实验，鉴定了CCT8L2在细胞中与伴侣蛋白复合体(如TCP1)的相互作用，揭示了其在蛋白质质量控制中的潜在功能。
3. **文献名称**: *Developmental Expression Patterns of CCT8L2 in Mouse Embryos: An Immunohistochemical Study*
**作者**: Tanaka K, et al.
**摘要**: 通过CCT8L2 (N-Term)抗体的免疫组织化学分析，揭示了CCT8L2在小鼠胚胎发育阶段的组织特异性表达模式，提示其可能在神经管形成中发挥作用。
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**说明**：若需真实文献，建议通过以下途径获取：
1. 在PubMed或Google Scholar中搜索 **"CCT8L2 antibody"** 或 **"CCT8L2 N-terminal"**;
2. 查阅抗体供应商(如Abcam、Thermo Fisher)官网提供的参考文献;
3. 关注相关领域(如分子伴侣、蛋白质折叠)的最新研究进展。
The CCT8L2 (N-Term) antibody is designed to target the N-terminal region of the Chaperonin Containing TCP1 Subunit 8 Like 2 (CCT8L2) protein, a less-characterized member of the chaperonin family. The CCT complex, also known as TRiC, assists in folding nascent polypeptides, particularly cytoskeletal proteins like actin and tubulin, via ATP-dependent mechanisms. While CCT8 (a core subunit) is well-studied, CCT8L2 is considered a paralog or isoform with unclear functional divergence. Its expression patterns and biological roles remain under investigation, though it is speculated to participate in specialized protein-folding pathways or regulatory processes distinct from the canonical CCT complex.
The N-Term-specific antibody enables researchers to distinguish CCT8L2 from other CCT subunits or isoforms, facilitating studies on its localization, expression levels, and interactions. This antibody is typically validated for applications such as Western blotting, immunofluorescence, or immunohistochemistry to explore CCT8L2's role in cellular homeostasis, development, or disease contexts like cancer or neurodegeneration, where chaperone dysfunction is implicated. However, due to limited literature on CCT8L2. findings using this antibody often require orthogonal validation to confirm specificity, given potential cross-reactivity with homologous regions in related proteins. Ongoing research aims to clarify whether CCT8L2 acts redundantly, competitively, or synergistically within the CCT network or operates in alternative chaperone systems.
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