| WB | 1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Zinc finger protein 513, ZNF513 |
| Entrez GeneID | 130557 |
| WB Predicted band size | 57.9kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This ZNF513 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 82-115 amino acids from human ZNF513. |
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以下是关于ZNF513(N-Term)抗体的3篇模拟参考文献示例(注：以下内容为示例，实际文献需通过学术数据库验证)：
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1. **文献名称**: *ZNF513 regulates retinal development through transcriptional activation of photoreceptor genes*
**作者**: Smith A, et al.
**摘要**: 本研究利用ZNF513(N-Term)抗体进行免疫沉淀和Western blot分析，发现ZNF513在视网膜发育中通过结合特定DNA序列激活光感受器基因(如RHO)，其缺失导致小鼠模型视网膜结构异常。
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2. **文献名称**: *Interaction of ZNF513 with SOX2 in neural progenitor cells revealed by ChIP-seq*
**作者**: Lee J, et al.
**摘要**: 通过ChIP-seq实验结合ZNF513(N-Term)抗体，作者鉴定出ZNF513与SOX2转录因子在神经前体细胞中的协同作用，调控神经分化相关基因的表达，提示其在神经发育中的关键角色。
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3. **文献名称**: *ZNF513 expression correlates with glioma progression and patient survival*
**作者**: Brown K, et al.
**摘要**: 使用ZNF513(N-Term)抗体进行免疫组化分析，发现ZNF513在高级别胶质瘤中高表达，且与患者预后不良显著相关，提示其作为潜在肿瘤标志物的可能性。
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**注**：以上为模拟参考文献，实际文献需查阅PubMed、Google Scholar等平台确认。建议以“ZNF513 antibody”、“N-Term”等关键词检索最新研究。
The ZNF513 (N-Term) antibody is a polyclonal or monoclonal antibody designed to detect the N-terminal region of zinc finger protein 513 (ZNF513), a member of the Krüppel-associated box (KRAB) domain-containing zinc finger protein family. These proteins are characterized by tandem C2H2-type zinc finger motifs involved in DNA binding and transcriptional regulation. ZNF513. also known as RNF165. is implicated in regulating gene expression during development, particularly in craniofacial and neural tissues. Studies suggest its role in modulating the SHH (Sonic Hedgehog) signaling pathway and interacting with other transcription factors to influence cell differentiation.
This antibody is commonly used in applications like Western blotting (WB), immunohistochemistry (IHC), and immunofluorescence (IF) to identify endogenous ZNF513 protein levels in human, mouse, or rat tissues. Its specificity for the N-terminal region ensures recognition of full-length or truncated isoforms containing this epitope. Research has linked ZNF513 dysfunction to developmental disorders and diseases, including certain retinal pathologies. Validations typically include knockdown experiments or peptide blocking to confirm binding specificity. As a tool, this antibody aids in exploring ZNF513's molecular mechanisms, tissue distribution, and potential therapeutic targets.
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