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Rabbit Polyclonal NAT16(N-Term) Antibody

  • 中文名: NAT16 (N-Term)抗体
  • 别    名: Putative N-acetyltransferase 16, 2.3.1.-, NAT16, C7orf52
货号: IPDX33811
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/2000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesPutative N-acetyltransferase 16, 2.3.1.-, NAT16, C7orf52
Entrez GeneID375607
WB Predicted band size40.5kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenThis NAT16 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-46 amino acids from human NAT16.

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参考文献

以下是模拟的关于NAT16(N-Term)抗体的参考文献示例。由于无法访问实时数据库,以下内容为假设性示例,实际文献需通过学术数据库验证:

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1. **文献名称**:*NAT16-Mediated N-Terminal Acetylation in Cell Proliferation*

**作者**:Smith A, et al.

**摘要**:研究NAT16在细胞周期调控中的作用,开发了一种特异性识别NAT16 N末端乙酰化修饰的抗体,证实其在癌症细胞模型中的表达变化。

2. **文献名称**:*Development of a Monoclonal Antibody Targeting NAT16 for Proteomic Analysis*

**作者**:Zhang L, et al.

**摘要**:报道了一种新型抗NAT16 N末端单克隆抗体的制备与验证,该抗体可用于免疫沉淀和质谱分析,揭示了NAT16与蛋白质稳态的关联。

3. **文献名称**:*N-Terminal Acetylation by NAT16 in Neurodegenerative Disorders*

**作者**:Brown K, et al.

**摘要**:通过NAT16特异性抗体检测阿尔茨海默病模型中的N末端乙酰化水平,探讨其与tau蛋白异常聚集的相关性。

4. **文献名称**:*Structural Insights into NAT16 and Antibody Recognition Mechanisms*

**作者**:Lee S, et al.

**摘要**:结合X射线晶体学分析NAT16的N末端结构,并解析了与其特异性结合的抗体的表位特征,为药物设计提供依据。

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**注意**:以上为模拟文献,实际研究中请通过PubMed、Google Scholar等平台以关键词“NAT16 antibody”“N-terminal acetylation”等检索最新文献。

背景信息

The NAT16 (N-Term) antibody is designed to target the N-terminal region of NAT16. a protein implicated in acetyltransferase activity and post-translational modifications. NAT16. also known as N-acetyltransferase 16. belongs to the GNAT (GCN5-related N-acetyltransferase) superfamily, which plays roles in diverse cellular processes, including gene regulation, metabolism, and stress responses. The N-terminal domain of NAT16 is critical for its enzymatic function, often involved in substrate recognition or protein-protein interactions. This antibody is commonly used in research to study NAT16 expression, localization, and molecular interactions via techniques like Western blotting, immunofluorescence, or immunoprecipitation. It is particularly valuable in exploring NAT16's role in cellular acetylation pathways, which may influence chromatin remodeling, protein stability, or metabolic regulation. Validated for specificity, the antibody helps identify NAT16 isoforms and assess its dysregulation in disease contexts, such as cancer or neurodegenerative disorders. Researchers rely on it to dissect NAT16's contribution to epigenetic mechanisms or stress adaptation, leveraging its specificity for the N-terminal epitope to avoid cross-reactivity with related acetyltransferases. Host species (e.g., rabbit or mouse) and clonality (monoclonal/polyclonal) may vary by product, but rigorous validation ensures reliable detection in model systems.

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