| WB | 1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Transmembrane protein adipocyte-associated 1, Integral membrane protein GPR175, Transmembrane protein 227, TPRA1, GPR175, TMEM227 |
| Entrez GeneID | 131601 |
| WB Predicted band size | 41.1kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This TPRA1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 16-47 amino acids from human TPRA1. |
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以下是关于TPRA1 (N-Term)抗体的3篇参考文献示例(注：TPRA1相关研究有限，以下内容为模拟示例，实际文献需通过学术数据库验证)：
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1. **文献名称**：*Characterization of TPRA1 N-Terminal Antibody in Cancer Cell Migration*
**作者**：Smith J, et al.
**摘要**：本研究开发了一种针对TPRA1蛋白N端的特异性抗体，验证了其在Western blot和免疫荧光中的应用。结果表明，TPRA1通过调控细胞骨架重组促进乳腺癌细胞迁移。
2. **文献名称**：*TPRA1 Interaction with MAPK Signaling Pathway Revealed by Immunoprecipitation*
**作者**：Zhang L, et al.
**摘要**：利用TPRA1 (N-Term)抗体进行免疫共沉淀实验，发现TPRA1与MAPK通路蛋白相互作用，提示其在细胞增殖和凋亡中的潜在作用。
3. **文献名称**：*Validation of a Novel TPRA1 Antibody for Immunohistochemical Staining in Glioblastoma*
**作者**：Johnson R, et al.
**摘要**：该研究验证了TPRA1 N端抗体在胶质母细胞瘤组织中的特异性染色，发现高表达TPRA1与患者预后不良相关，为癌症生物标志物研究提供工具。
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**注意**：上述文献为示例，实际研究中TPRA1相关公开文献较少，建议通过**PubMed**或**Google Scholar**以“TPRA1 antibody”或“TPRA1 N-terminal”为关键词检索最新进展。如需商业抗体信息，可参考厂商资料(如Santa Cruz Biotechnology或Abcam的产品说明)。
The TPRA1 (N-Term) antibody is a specific immunological tool designed to target the N-terminal region of the TPRA1 protein (also known as transmembrane protein 40. TMEM40). TPRA1 is a poorly characterized, evolutionarily conserved protein localized to the endoplasmic reticulum (ER) and nuclear envelope. It is hypothesized to play a role in maintaining ER structure, lipid metabolism, or membrane dynamics, though its precise molecular functions remain under investigation. Studies suggest potential involvement in cellular processes like apoptosis, autophagy, and cancer progression, with altered expression observed in certain tumors.
The TPRA1 (N-Term) antibody is commonly used in research applications such as Western blotting, immunofluorescence, and immunohistochemistry to detect endogenous TPRA1 protein levels in human, mouse, or rat samples. Its specificity for the N-terminal epitope allows differentiation from potential splice variants or degradation products. Researchers employ this antibody to explore TPRA1's tissue distribution, subcellular localization, and expression patterns under physiological or pathological conditions. Validation typically includes knockdown/knockout controls to confirm signal specificity. As TPRA1 gains attention in fields like cancer biology and organelle dynamics, this antibody serves as a critical reagent for elucidating its biological roles and therapeutic potential.
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