| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Condensin-2 complex subunit G2, Chromosome-associated protein G2, CAP-G2, hCAP-G2, Leucine zipper protein 5, Non-SMC condensin II complex subunit G2, NCAPG2, LUZP5 |
| Entrez GeneID | 54892 |
| WB Predicted band size | 131.0kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This NCAPG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 729-757 amino acids from the Central region of human NCAPG2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于NCAPG2抗体的模拟参考文献示例(注：以下内容为示例，实际文献需通过学术数据库核实)：
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1. **标题**: *NCAPG2 overexpression correlates with poor prognosis in hepatocellular carcinoma: an immunohistochemical study*
**作者**: Zhang L, et al.
**摘要**: 本研究通过免疫组化技术使用NCAPG2抗体检测肝癌组织中蛋白表达水平，发现NCAPG2高表达与患者总生存期缩短显著相关，提示其可能作为肝癌预后标志物。
2. **标题**: *NCAPG2 regulates mitotic chromosome condensation via interaction with topoisomerase IIα*
**作者**: Smith J, et al.
**摘要**: 利用NCAPG2抗体进行免疫沉淀和蛋白质印迹实验，揭示了NCAPG2通过结合拓扑异构酶IIα调控染色体凝聚的分子机制，为细胞周期研究提供新见解。
3. **标题**: *NCAPG2 as a potential therapeutic target in triple-negative breast cancer*
**作者**: Wang Y, et al.
**摘要**: 通过NCAPG2抗体抑制实验及基因沉默技术，证明靶向NCAPG2可抑制三阴性乳腺癌细胞增殖并诱导凋亡，提示其治疗潜力。
4. **标题**: *Development and validation of a novel NCAPG2 monoclonal antibody for clinical diagnostics*
**作者**: Kim H, et al.
**摘要**: 报道了一种新型NCAPG2单克隆抗体的开发，经ELISA和免疫荧光验证其特异性，可用于癌症组织病理诊断及血清标志物检测。
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建议通过PubMed、Web of Science等平台以关键词“NCAPG2 antibody”或“NCAPG2 immunohistochemistry”检索最新文献，获取真实研究数据。
The NCAPG2 (Non-SMC Condensin II Complex Subunit G2) antibody is a crucial tool for studying the role of NCAPG2. a protein integral to chromosome organization and segregation during cell division. NCAPG2 is a core component of the condensin II complex, which regulates chromosome condensation, mitotic progression, and genome stability. Dysregulation of NCAPG2 has been linked to chromosomal instability, abnormal cell cycle regulation, and carcinogenesis. Overexpression of NCAPG2 is observed in various cancers, including hepatocellular carcinoma, lung adenocarcinoma, and breast cancer, where it correlates with poor prognosis, tumor proliferation, and metastasis.
The NCAPG2 antibody enables researchers to detect and quantify NCAPG2 expression in tissues or cell lines via techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). It aids in exploring NCAPG2's functional mechanisms in chromatin dynamics, its interaction with other condensin II subunits, and its potential as a diagnostic or prognostic biomarker. Recent studies also investigate its role in DNA repair and response to chemotherapy. Validated for specificity and sensitivity in multiple species, this antibody supports both basic research and translational studies targeting NCAPG2-related pathways in cancer and developmental disorders.
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