Cat: PA1000-9601

Recombinant Human PPHLN1 Protein,His

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关键信息

  • 基因名

    PPHLN1

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    PPHLN1;Periphilin-1

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q8NEY8

  • 表达区间

    1-458aa

  • 氨基酸序列

    MWSEGRYEYE RIPRERAPPR SHPSDGYNRL VNIVPKKPPL LDRPGEGSYN RYYSHVDYRD YDEGRSFSHD RRSGPPHRGD ESGYRWTRDD HSASRQPEYR DMRDGFRRKS FYSSHYARER SPYKRDNTFF RESPVGRKDS PHSRSGSSVS SRSYSPERSK SYSFHQSQHR KSVRPGASYK RQNEGNPERD KERPVQSLKT SRDTSPSSGS AVSSSKVLDK PSRLTEKELA EAASKWAAEK LEKSDESNLP EISEYEAGST APLFTDQPEE PESNTTHGIE LFEDSQLTTR SKAIASKTKE IEQVYRQDCE TFGMVVKMLI EKDPSLEKSI QFALRQNLHE IESAGQTWQQ VPPVRNTEMD HDGTPENEGE ETAQSAPQPP QAPQPLQPRK KRVRRTTQLR RTTGAPDITW GMLKKTTQEA ERILLRTQTP FTPENLFLAM LSVVHCNSRK DVKPENKQ

  • 分子量

    52.7 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

PPHLN1 (Pseudopodium Formation Protein in Leucine-Rich Repeat-Containing 1) is a protein that plays a crucial role in neuronal development and function. Recent studies have indicated that PPHLN1 is involved in neuronal differentiation, synaptic plasticity, and may influence various neurological disorders. Its unique structure, characterized by leucine-rich repeats, suggests potential interactions with various cellular signaling pathways. Due to its importance in neurobiology, there is increasing interest in exploring PPHLN1 as a target for therapeutic interventions in conditions such as autism spectrum disorders and schizophrenia. Furthermore, the recombinant expression of PPHLN1 provides a valuable tool for investigating its biochemical properties, cellular localization, and interaction with other proteins. By producing recombinant PPHLN1, researchers aim to elucidate its functional mechanisms and assess its potential as a biomarker or therapeutic candidate in neurodevelopmental and psychiatric disorders. Understanding the role of PPHLN1 could pave the way for novel treatment strategies, emphasizing the need for continued research in this promising area of neuroscience.

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