Rabbit Polyclonal PPP1R3F Antibody

The PPP1R3F antibody is a research tool designed to detect Protein Phosphatase 1 Regulatory Subunit 3F (PPP1R3F), a member of the protein phosphatase 1 (PP1) regulatory subunit family. PP1 phosphatases regulate diverse cellular processes, including glycogen metabolism, cell cycle progression, and signal transduction, by dephosphorylating target proteins. PPP1R3F acts as a regulatory subunit that directs PP1 activity toward specific substrates, particularly in glycogen metabolism pathways. It shares homology with other PPP1R3 family members (e.g., PPP1R3A–D), which exhibit tissue-specific expression and functional roles. PPP1R3F is less characterized compared to its homologs but is implicated in modulating glycogen synthase activity and glucose homeostasis. Studies suggest its potential involvement in metabolic disorders, such as diabetes, and cancer due to links between metabolic reprogramming and tumor progression. The PPP1R3F antibody is commonly used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to study its expression patterns, subcellular localization, and interactions in cell lines or tissues. Its development aids in elucidating PPP1R3F’s physiological roles and its relevance to disease mechanisms, though further research is needed to fully define its regulatory networks and clinical significance.