WB | 1/2000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | T-cell leukemia translocation-altered gene protein, T-cell leukemia translocation-associated gene protein, TCTA |
Entrez GeneID | 6988 |
WB Predicted band size | 11.3kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | This TCTA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 23-55 amino acids from human TCTA. |
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以下是关于TCTA (N-Term)抗体的参考文献示例(内容为模拟,仅供参考):
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1. **"A novel monoclonal antibody targeting the N-terminal domain of TCTA (ARID3B) reveals its nuclear localization in cancer cells"**
*Authors: Smith J, et al.*
摘要:本研究开发了一种特异性识别TCTA蛋白N端结构域的单克隆抗体,验证了其在Western blot和免疫荧光中的高特异性,并发现TCTA在多种癌细胞核中异常表达,可能与转录调控相关。
2. **"Functional characterization of TCTA in hematopoiesis using N-terminal specific antibodies"**
*Authors: Tanaka K, et al.*
摘要:通过针对TCTA N端的抗体,研究证实其在造血干细胞分化中的关键作用,抗体通过阻断N端功能域抑制了白血病细胞的增殖,提示其作为治疗靶点的潜力。
3. **"Development of a polyclonal anti-TCTA (N-Term) antibody for detecting epigenetic modifications in solid tumors"**
*Authors: Lee S, et al.*
摘要:报道了一种兔源多克隆抗体的制备,特异性靶向TCTA的N端表位,应用于免疫组化分析,显示TCTA在乳腺癌和肺癌组织中的表达与患者预后显著相关。
4. **"TCTA/ARID3B N-terminal interactions: structural insights from antibody-mediated inhibition assays"**
*Authors: Garcia-Ruiz C, et al.*
摘要:利用N端抗体研究TCTA的蛋白互作网络,发现其N端结构域与染色质重塑复合物结合,为解析TCTA在基因沉默中的机制提供了新证据。
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*注:以上文献为示例性质,实际引用请通过学术数据库(如PubMed、Web of Science)检索真实发表的研究。*
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