Rabbit Polyclonal CIDEB(C-erm) Antibody

The CIDEB (CIDE domain-containing protein B), also known as C-erm, is a member of the cell death-inducing DFFA-like effector (CIDE) family, which plays a critical role in lipid metabolism and droplet dynamics. Primarily expressed in the liver and adipose tissue, CIDEB facilitates lipid droplet fusion and regulates lipid storage, impacting systemic energy homeostasis. Its dysfunction is linked to metabolic disorders, including non-alcoholic fatty liver disease (NAFLD) and hepatic steatosis. The CIDEB (C-erm) antibody specifically targets the C-terminal region of the protein, enabling researchers to study its expression, localization, and interaction partners in cellular and tissue contexts. This antibody is widely utilized in techniques such as Western blotting, immunohistochemistry, and immunofluorescence to investigate CIDEB's role in lipid metabolism pathways, disease mechanisms, and potential therapeutic targets. Recent studies highlight CIDEB's involvement in hepatitis B virus infection and its crosstalk with insulin signaling, underscoring its broader relevance in metabolic and infectious diseases. As a research tool, the CIDEB antibody aids in elucidating molecular pathways driving lipid-related pathologies, offering insights for developing interventions targeting obesity, diabetes, and liver diseases.