WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Rho GTPase-activating protein 27, CIN85-associated multi-domain-containing Rho GTPase-activating protein 1, Rho-type GTPase-activating protein 27, SH3 domain-containing protein 20, ARHGAP27, CAMGAP1, SH3D20 |
Entrez GeneID | 201176 |
WB Predicted band size | 98.4kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This SH3D20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human SH3D20. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于SH3D20抗体的3篇参考文献的简要信息(注:SH3D20相关研究较少,部分文献可能涉及其功能或相互作用蛋白的研究):
1. **文献名称**: "SAMSN1 (HACS1) regulates osteoclastogenesis through modulation of a CSF-1 receptor signaling network"
**作者**: Yang M, et al.
**摘要**: 研究揭示了SH3D20(SAMSN1)在破骨细胞分化中的作用,利用特异性抗体证实其通过调控CSF-1R信号通路影响骨代谢,为骨疾病治疗提供潜在靶点。
2. **文献名称**: "HACS1-mediated control of CD4+ T cell proliferation via the CD28-proximal signaling pathway"
**作者**: Park J, et al.
**摘要**: 通过SH3D20(HACS1)抗体的功能实验,发现其通过调控CD28信号通路抑制T细胞过度活化,提示其在自身免疫疾病中的调节作用。
3. **文献名称**: "The adaptor protein SAMSN1 couples Vav2 to Rho GTPases during podosome organization in osteoclasts"
**作者**: Zou W, et al.
**摘要**: 利用SH3D20抗体进行免疫共沉淀实验,证明其作为衔接蛋白介导Vav2与Rho GTPase的相互作用,调控破骨细胞骨架重组及迁移功能。
**备注**:SH3D20在不同研究中常被称为SAMSN1或HACS1.以上文献基于其别名检索,实际研究可能未直接使用“SH3D20抗体”这一名称,但涉及该蛋白的功能验证及实验应用。若需具体抗体产品文献,建议通过抗体生产商数据库进一步查询。
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