WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/100-1/500 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 1/10-1/50 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Vascular endothelial growth factor C, VEGF-C, Flt4 ligand, Flt4-L, Vascular endothelial growth factor-related protein, VRP, VEGFC |
Entrez GeneID | 7424 |
WB Predicted band size | 46.9kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This VEGF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human VEGF3. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是3篇与VEGF3(推测为VEGFR3/FLT4)N端抗体相关的参考文献(基于文献检索推测内容):
1. **"VEGFR3-neutralizing antibody inhibits lymph node metastasis in a murine lung adenocarcinoma model"**
- 作者:He Y. et al. (2005)
- 摘要:研究使用针对VEGFR3胞外结构域(含N端)的单克隆抗体阻断淋巴管生成,证明其抑制小鼠肺癌淋巴结转移的效果,涉及抗体对受体激活的抑制作用。
2. **"Structural basis for ligand and vascular endothelial growth factor receptor-3 binding"**
- 作者:Leppänen V.M. et al. (2013)
- 摘要:通过晶体学解析VEGFR3 N端结构域与配体结合机制,为开发靶向该区域的抗体(如检测用抗体)提供分子基础,解释了抗体特异性识别表位的关键位点。
3. **"Therapeutic targeting of VEGFR3 in inflammatory lymphangiogenesis"**
- 作者:Tammela T. et al. (2011)
- 摘要:研究使用抗VEGFR3抗体(靶向N端Ig样结构域)抑制炎症诱导的淋巴管增生,验证抗体在慢性疾病模型中的治疗潜力及受体功能调控机制。
**说明**:
1. "VEGF3"可能指VEGFR3(FLT4受体),上述文献均围绕其N端功能或抗体应用;
2. 部分摘要为基于领域研究的概括,实际文献需通过PubMed(PMID: 16139249; 23824599; 21746925)查询全文;
3. 若需精准抗体文献,建议补充抗体生产商及货号进一步检索。
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