Cat: IPD-X41814

Recombinant Human SLC25A19 Protein,His

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关键信息

  • 基因名

    SLC25A19

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    (Mitochondrial uncoupling protein 1)(Solute carrier family 25 member 19)

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N- His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9HC21

  • 表达区间

    1-320aa

  • 分子量

    37.0 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

SLC25A19 is a gene that encodes for a mitochondrial transporter protein involved in the transport of key metabolites, particularly in the context of cellular energy metabolism. Mutations in this gene have been linked to various metabolic disorders, including mitochondrial diseases, which can severely affect organ function and overall health. Research into SLC25A19 has gained significance due to its role in the pathophysiology of conditions such as mitochondrial encephalomyopathy, which emphasizes the importance of understanding its functional mechanisms. The recombinant protein produced from SLC25A19 is a valuable tool for investigating its transport capabilities, substrate specificity, and interactions with other mitochondrial proteins. Through detailed biochemical and structural studies, researchers aim to elucidate the molecular basis of SLC25A19 function and its implications in health and disease. Such insights are critical for developing potential therapeutic strategies targeting mitochondrial dysfunction, thereby enhancing our understanding of cellular energy homeostasis and its impact on human health.

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