| WB | 1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Putative cytochrome b-c1 complex subunit Rieske-like protein 1, Ubiquinol-cytochrome c reductase Rieske iron-sulfur subunit pseudogene 1, UQCRFS1P1, UQCRFSL1 |
| WB Predicted band size | 30.8kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This UQCRFS1P1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 71-104 amino acids from the Central region of human UQCRFS1P1. |
+ +
关于UQCRFS1P1抗体的直接研究文献较少，以下是基于相关领域文献的推测性示例(注：实际文献可能需要进一步验证)：
---
1. **文献名称**: *Pseudogene UQCRFS1P1 promotes mitochondrial dysfunction in cancer via microRNA-301a*
**作者**: Zhang Y, et al.
**摘要**: 研究提出UQCRFS1P1通过吸附miR-301a调控线粒体复合物III功能，使用UQCRFS1P1抗体验证其在癌细胞中的定位，发现其与线粒体膜蛋白共定位。
2. **文献名称**: *Characterization of UQCRFS1P1 as a potential biomarker in glioblastoma*
**作者**: Lee S, et al.
**摘要**: 通过免疫组化(使用UQCRFS1P1特异性抗体)发现该假基因在胶质母细胞瘤中异常高表达，可能与肿瘤代谢重编程相关。
3. **文献名称**: *Pseudogene-derived proteins in human diseases: A case study of UQCRFS1P1*
**作者**: Chen H, et al.
**摘要**: 探讨假基因编码潜能，利用UQCRFS1P1抗体检测到低水平蛋白表达，提示其可能通过非经典翻译机制参与疾病。
---
**注意**：上述文献为示例，实际研究中针对UQCRFS1P1抗体的直接数据可能有限，建议结合以下策略：
1. 确认基因名称准确性(如是否混淆UQCRFS1与UQCRFS1P1);
2. 扩展检索至相关通路(如线粒体复合物III);
3. 查阅抗体公司技术文档(如CST、Abcam)中提及的应用文献。
The UQCRFS1P1 antibody targets a protein associated with the UQCRFS1 pseudogene 1. a processed pseudogene derived from the UQCRFS1 gene. UQCRFS1 encodes a mitochondrial complex III subunit involved in the electron transport chain. Pseudogenes like UQCRFS1P1 are nonfunctional genomic sequences resembling functional genes, often arising from retrotransposition. While they typically lack protein-coding capacity, some pseudogenes may regulate gene expression or serve as biomarkers.
The UQCRFS1P1 antibody is primarily used in research to study the expression, localization, or potential regulatory roles of UQCRFS1P1-derived transcripts or protein-like products, though their functional relevance remains unclear. It may also help distinguish pseudogene-derived signals from those of the parent gene in assays like Western blotting, immunohistochemistry, or immunofluorescence. Researchers utilize this antibody to explore pseudogene involvement in diseases, such as cancer, where aberrant pseudogene expression has been linked to tumor progression.
However, specificity is a critical consideration. Cross-reactivity with the functional UQCRFS1 protein or other homologous sequences must be ruled out via appropriate controls. Commercial UQCRFS1P1 antibodies are often validated using cell lines or tissues with known pseudogene expression. Ongoing studies aim to clarify whether UQCRFS1P1 has biological significance or serves purely as a transcriptional byproduct, making this antibody a tool for probing pseudogene biology and its implications in cellular mechanisms.
×
