Rabbit Polyclonal FAM189B Antibody

The FAM189B antibody is a tool used to detect FAM189B, a protein encoded by the FAM189B gene (Family with Sequence Similarity 189 Member B). FAM189B is a poorly characterized protein, but emerging studies suggest it may play roles in cellular adhesion, signaling, or neurodevelopmental processes. It shares structural homology with FAM189A, which is implicated in membrane dynamics and cell-cell interactions. The FAM189B antibody, typically developed in rabbit or mouse hosts, enables researchers to study the protein's expression, localization, and function. It is commonly validated in applications like Western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF), often showing reactivity in human or murine tissues. While FAM189B's exact biological significance remains unclear, its expression patterns in the brain, testes, and certain cancers (e.g., gliomas) hint at potential roles in neural development, reproduction, or tumorigenesis. Commercial antibodies often include validation data (e.g., knockout cell line controls) to confirm specificity. Research using this antibody is still exploratory, focusing on mapping protein interactions and tissue distribution to uncover mechanistic insights. Its study may contribute to understanding diseases linked to cell adhesion defects or neurological disorders.