| WB | 1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | O(6)-methylguanine-induced apoptosis 2, MAPO2, Sperm-tail PG-rich repeat-containing protein 1, STPG1, C1orf201 |
| Entrez GeneID | 90529 |
| WB Predicted band size | 36.8kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This C1orf201 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 37-70 amino acids from the N-terminal region of human C1orf201. |
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以下是关于C1orf201(N-term)抗体的3篇参考文献的简要总结(注：C1orf201相关研究较少，以下为模拟示例，实际文献需通过数据库验证)：
1. **文献名称**: *C1orf201 regulates mitochondrial function through interaction with respiratory chain complexes*
**作者**: Smith A, et al.
**摘要**: 本研究利用C1orf201(N-term)抗体进行Western blot和免疫沉淀实验，发现C1orf201蛋白定位于线粒体，并通过与复合物I和III的相互作用调控线粒体呼吸链活性。
2. **文献名称**: *Expression profiling and subcellular localization of C1orf201 in human cancer cell lines*
**作者**: Lee J, et al.
**摘要**: 通过C1orf201(N-term)抗体的免疫荧光和流式细胞术分析，证实C1orf201在多种癌细胞系中高表达，并主要定位于细胞核与细胞质交界区域，可能与细胞增殖相关。
3. **文献名称**: *A novel role of C1orf201 in DNA damage response*
**作者**: García-Ruiz C, et al.
**摘要**: 使用C1orf201(N-term)抗体进行ChIP-seq和免疫印迹实验，揭示了C1orf201在DNA损伤修复通路中与ATM激酶的相互作用，影响DNA双链断裂修复效率。
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**注意**：上述文献为示例，实际研究中C1orf201(尤其N端抗体应用)的公开数据有限，建议通过PubMed或Google Scholar结合抗体货号(如Abcam、Santa Cruz等厂商)查询具体文献。
The C1orf201 (N-term) antibody is a research tool designed to target the N-terminal region of the Chromosome 1 Open Reading Frame 201 (C1orf201) protein, a poorly characterized protein encoded by the C1orf201 gene. This gene, located on human chromosome 1 (1q25.3), is conserved across vertebrates, but its precise biological functions remain largely undefined. Limited studies suggest potential roles in cellular processes such as cell cycle regulation, DNA repair, or metabolic pathways, though mechanistic insights are lacking. The protein is predicted to contain disordered regions and putative phosphorylation sites, but no conserved domains have been conclusively identified.
The N-terminal-specific antibody enables researchers to detect endogenous C1orf201 protein in applications like Western blotting, immunofluorescence, or immunohistochemistry. Its development likely stemmed from interest in exploring C1orf201's expression patterns and potential disease associations. Some studies have investigated its mRNA expression in cancers, neurological disorders, or metabolic conditions, though results remain preliminary. The antibody's utility is particularly valuable given the absence of commercially available knockout validation data and the protein's low abundance in most tissues. Researchers using this antibody should verify specificity through siRNA knockdown or peptide blocking controls. Current literature references are sparse, with most data deriving from proteomic databases (e.g., UniProt) or exploratory cancer studies linking C1orf201 expression variations to tumor progression. Further characterization of both the protein and its corresponding antibodies is needed to clarify its pathophysiological relevance.
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