| WB | 1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Transformation/transcription domain-associated protein, Tra1 homolog, Trrap |
| WB Predicted band size | 291.6kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This mouse Trrap antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1703-1737 amino acids from the C-terminal region of mouse Trrap. |
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以下是基于假设的示例性参考文献(注：以下内容为虚构示例，实际文献需通过学术数据库检索确认)：
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1. **文献名称**: "Development of a High-Affinity Monoclonal Antibody Targeting Mouse TRAP for Osteoclast Inhibition"
**作者**: Smith A, et al.
**摘要**: 研究报道了一种针对小鼠抗酒石酸酸性磷酸酶(TRAP)的单克隆抗体开发，通过噬菌体展示技术筛选高亲和力抗体，证实其可有效抑制破骨细胞活性，可能用于骨质疏松症治疗。
2. **文献名称**: "TRAP Antibody-Based Detection of Tumor Microenvironment in Mouse Models"
**作者**: Chen L, et al.
**摘要**: 利用抗小鼠TRAP抗体标记肿瘤微环境中的巨噬细胞，结合免疫组化技术分析癌症模型中的基质重塑机制，揭示TRAP表达与肿瘤转移的相关性。
3. **文献名称**: "A Novel TRAP-Specific Nanobody for In Vivo Imaging in Mice"
**作者**: Gupta R, et al.
**摘要**: 开发了一种靶向TRAP的纳米抗体，通过近红外成像技术实现小鼠体内破骨细胞活性的实时动态监测，为骨代谢疾病提供新型诊断工具。
4. **文献名称**: "Cross-Reactivity Analysis of Anti-Mouse TRAP Antibodies in Human Samples"
**作者**: Tanaka K, et al.
**摘要**: 评估了多种商业抗小鼠TRAP抗体与人源TRAP的交叉反应性，发现部分抗体存在种属特异性差异，为跨物种研究提供实验设计参考。
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如需真实文献，建议在 **PubMed** 或 **Google Scholar** 检索关键词：
`mouse TRAP antibody`, `tartrate-resistant acid phosphatase antibody`, `osteoclast antibody`。
The Mouse Trrap (Transformation/transcription domain-associated protein) antibody is designed to detect and study the Trrap protein, a critical transcriptional cofactor involved in chromatin remodeling and DNA damage response. Trrap serves as an essential component of histone acetyltransferase (HAT) complexes, including the Tip60 and PCAF complexes, which acetylate histones to modulate chromatin structure and regulate gene expression. It interacts with transcription factors such as c-Myc, E2F, and p53. playing roles in cell cycle progression, apoptosis, and oncogenesis. Trrap also participates in DNA repair mechanisms by recruiting repair proteins to sites of damage.
Research using Mouse Trrap antibodies typically focuses on elucidating its role in transcriptional regulation, genomic stability, and cancer biology. These antibodies are employed in techniques like Western blotting, immunofluorescence, and immunoprecipitation to assess Trrap expression, localization, and protein interactions in murine models. Given Trrap’s involvement in embryonic development and its dysregulation in cancers, such antibodies are valuable tools for studying disease mechanisms and potential therapeutic targets. Their specificity for murine Trrap ensures relevance in preclinical studies using mouse models to mimic human pathologies.
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