Rabbit Polyclonal AQPEP Antibody

The AQPEP antibody targets alanyl aminopeptidase, putative (AQPEP), a protein belonging to the M1 zinc-dependent metallopeptidase family. AQPEP is implicated in the cleavage of N-terminal amino acids from bioactive peptides, potentially regulating their stability and activity. It is expressed in tissues such as the kidney, intestine, and brain, where it may influence processes like peptide hormone metabolism, blood pressure regulation, and neuropeptide signaling. AQPEP antibodies are primarily used in research to detect and localize the protein via techniques like immunohistochemistry, Western blotting, and flow cytometry. Studies suggest AQPEP's involvement in pathophysiological conditions, including hypertension, inflammatory diseases, and cancer progression, though its precise mechanisms remain under investigation. The antibody serves as a critical tool for elucidating AQPEP's role in cellular homeostasis and disease, with potential implications for biomarker discovery or therapeutic targeting. Its specificity and validation across experimental models (e.g., human, mouse) make it valuable for comparative studies. Ongoing research aims to clarify AQPEP's interactions with substrates like vasopressin or angiotensin derivatives, which could deepen understanding of its physiological and pathological relevance.