Rabbit Polyclonal (DANRE)bhlha9(N-term) Antibody

The DANRE (Bhlha9) N-term antibody is a polyclonal or monoclonal antibody specifically designed to target the N-terminal region of Bhlha9 (Basic Helix-Loop-Helix Family Member A9), a transcription factor belonging to the basic helix-loop-helix (bHLH) protein family. Bhlha9. also known as Mist1 in mice or Capsulin in humans, plays critical roles in cell differentiation, tissue development, and organogenesis, particularly in secretory epithelial cells (e.g., pancreatic acinar cells, salivary glands) and skeletal muscle progenitors. The antibody is commonly used in molecular biology research to detect Bhlha9 expression via techniques like Western blotting, immunohistochemistry (IHC), or immunofluorescence (IF). Its N-terminal specificity ensures recognition of full-length or truncated isoforms, aiding studies on Bhlha9’s regulatory functions in developmental pathways, cellular identity maintenance, and diseases (e.g., pancreatitis, cancer). Developed in hosts such as rabbits or mice, it is often validated using knockout controls to confirm specificity. Researchers utilize this tool to explore Bhlha9’s role in tissue regeneration, tumorigenesis, and transcriptional networks, particularly in model organisms like zebrafish (Danio rerio, hence "DANRE") or mice. Its applications extend to developmental biology, oncology, and regenerative medicine.