| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Transmembrane protein 160, TMEM160 |
| Entrez GeneID | 54958 |
| WB Predicted band size | 19.7kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This TMEM160 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-64 amino acids from the N-terminal region of human TMEM160. |
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以下是3条关于TMEM160 (N-term)抗体的虚构参考文献示例(仅供参考，实际文献需根据具体研究检索)：
1. **文献名称**: "TMEM160 N-terminal antibody validates mitochondrial localization in apoptotic regulation"
**作者**: Smith J, et al.
**摘要**: 本研究利用TMEM160 N-term特异性抗体进行Western blot和免疫组化，证实该蛋白定位于线粒体外膜，并发现其在紫外线诱导的细胞凋亡中通过调控Bcl-2家族蛋白表达参与调控过程。
2. **文献名称**: "Characterization of a novel anti-TMEM160 (N-term) antibody for autophagy studies"
**作者**: Zhang Y, et al.
**摘要**: 文章报道了一种高特异性TMEM160 N端多克隆抗体的开发，通过siRNA敲除实验验证抗体特异性，并应用于免疫荧光技术，揭示TMEM160与自噬体标记蛋白LC3的共定位，提示其参与内质网-自噬体膜接触机制。
3. **文献名称**: "TMEM160 expression profiling in colorectal cancer using N-terminal targeted antibodies"
**作者**: Lee H, et al.
**摘要**: 研究使用TMEM160 N-term单克隆抗体对200例结直肠癌组织进行免疫组化分析，发现TMEM160高表达与患者总生存期延长显著相关，提示其可能作为抑癌生物标志物，抗体特异性通过质谱数据验证。
注：以上内容为模拟生成，实际文献需通过PubMed/Google Scholar以关键词"TMEM160 antibody N-terminal"或结合具体研究领域进行检索。若研究较少，可扩展检索TMEM160功能研究并核查抗体使用情况。
The TMEM160 (N-term) antibody is a research tool designed to detect the N-terminal region of transmembrane protein 160 (TMEM160), a poorly characterized protein implicated in cellular processes such as mitochondrial function and membrane organization. TMEM160 is predicted to contain multiple transmembrane domains, suggesting it may act as a channel, transporter, or structural component within membranes. While its exact biological role remains unclear, studies associate TMEM160 with mitochondrial dynamics, autophagy, and cellular stress responses. It has been observed in mitochondria-associated membranes (MAMs), where cross-talk between mitochondria and the endoplasmic reticulum occurs, hinting at potential roles in lipid metabolism or calcium signaling.
This antibody is commonly used in techniques like Western blotting, immunofluorescence, and immunohistochemistry to study TMEM160 expression, localization, and interactions. Researchers utilize it to explore TMEM160's involvement in diseases, including cancer and neurodegenerative disorders, where mitochondrial dysfunction is a hallmark. For instance, altered TMEM160 expression has been reported in certain tumors, though its clinical significance requires further validation. The N-terminal specificity of the antibody helps distinguish TMEM160 from related proteins or isoforms, provided proper validation (e.g., knockout controls) confirms its selectivity. Current research focuses on elucidating TMEM160's molecular partners and pathways, aiming to clarify its physiological and pathological relevance.
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