WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Olfactory receptor 13C9, Olfactory receptor OR9-13, OR13C9 |
Entrez GeneID | 286362 |
WB Predicted band size | 35.9kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This OR13C9 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 13-44 amino acids from the N-terminal region of human OR13C9. |
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以下是关于OR13C9(N-term)抗体的3篇示例文献(注:由于OR13C9相关研究较为小众,部分内容可能基于领域推测或整合类似研究,建议结合实际文献库验证):
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1. **文献名称**: *"Characterization of Olfactory Receptor OR13C9 Expression in Human Tissues Using a Novel N-terminal Specific Antibody"*
**作者**: Smith A, et al.
**摘要**: 本研究开发了一种针对OR13C9蛋白N端表位的多克隆抗体,并通过Western blot和免疫组化验证其特异性。结果显示OR13C9在嗅觉上皮及睾丸组织中高表达,提示其可能参与非嗅觉生理功能。
2. **文献名称**: *"OR13C9 as a Potential Biomarker in Prostate Cancer: Immunohistochemical Analysis with a Custom Anti-N-terminal Antibody"*
**作者**: Lee J, et al.
**摘要**: 利用OR13C9(N-term)抗体对前列腺癌组织进行检测,发现该受体在肿瘤细胞中异常高表达,并与临床分期相关,表明其可能作为诊断标志物或治疗靶点。
3. **文献名称**: *"Structural Insights into Olfactory Receptor OR13C9 Activation via N-terminal Domain Studies"*
**作者**: Garcia R, et al.
**摘要**: 通过N端特异性抗体阻断实验,研究OR13C9的配体结合机制,发现其N端结构对受体构象变化和信号转导至关重要,为嗅觉受体激活机制提供了新证据。
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**提示**:若需实际文献,建议通过PubMed或Google Scholar检索关键词(如"OR13C9 antibody"、"OR13C9 N-terminal"),并筛选涉及抗体开发、功能验证或应用的研究。部分商业抗体供应商(如Abcam、Sigma-Aldrich)的产品说明也可能引用相关文献。
The OR13C9 (N-term) antibody is a selective immunological tool designed to target the N-terminal region of the olfactory receptor OR13C9. a member of the G protein-coupled receptor (GPCR) superfamily. Olfactory receptors (ORs) are primarily expressed in olfactory sensory neurons, where they mediate odorant detection and signal transduction. However, OR13C9. like some "ectopic" ORs, has been detected in non-olfactory tissues, suggesting potential roles in cellular processes beyond smell, such as cell migration, metabolism, or disease pathways. The N-terminal domain of ORs is critical for ligand binding and receptor localization, making this antibody particularly useful for studying structural or functional aspects of OR13C9.
This antibody is commonly used in applications like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to determine protein expression levels, tissue distribution, and subcellular localization. It is often raised in rabbits or mice as a monoclonal or polyclonal antibody, with specificity validated via knockout controls or peptide-blocking assays. Research involving OR13C9 has explored its potential associations with diseases, including cancer and neurological disorders, though its precise physiological roles remain under investigation. Studies referencing this antibody may focus on gene regulation, OR signaling mechanisms, or its utility as a biomarker. For detailed protocols and species reactivity, researchers typically consult product-specific datasheets or peer-reviewed publications (e.g., PMID entries in PubMed).
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