Cat: IPD-X40614

Recombinant Human RAB3C Protein ,His & SUMO

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  • 规格
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关键信息

  • 基因名

    RAB3C

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    RAB3C; RAB3C member RAS oncogene family; RAB3C_HUMAN; Ras related protein Rab3C; Ras-related protein Rab-3C

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N- His-SUMO

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q96E17

  • 表达区间

    1-227aa

  • 分子量

    42 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

RAB3C is a member of the Rab family of small GTPases, which play essential roles in intracellular vesicular transport and membrane trafficking. Recent studies have highlighted the significance of RAB3C in neurotransmitter release, exocytosis, and the regulation of synaptic vesicles in neuronal cells. Its involvement in various biological processes, including synaptic plasticity, has made it a focus of research in neurobiology and related fields. Additionally, mutations and dysregulation of RAB proteins, including RAB3C, have been implicated in various neurological disorders, such as autism spectrum disorders and schizophrenia. Researchers have sought to investigate the structure and function of RAB3C through recombinant protein techniques, enabling the study of its biochemical properties and interactions with other molecules. These studies provide insights into the molecular mechanisms by which RAB3C influences synaptic function and pathology, paving the way for potential therapeutic interventions targeting related signaling pathways. Overall, the ongoing research into RAB3C recombinant protein promotes a deeper understanding of its crucial role in cellular communication and neurodevelopmental processes.

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