| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 1/25 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Far upstream element-binding protein 3, FUSE-binding protein 3, FUBP3, FBP3 |
| Entrez GeneID | 8939 |
| WB Predicted band size | 61.4kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified His-tagged FUBP3 protein was used to produced this monoclonal antibody. |
| Formulation | Purified antibody in TBS with 0.05% sodium azide. |
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以下是关于FUBP3 (N-term)抗体的3篇参考文献示例(注：部分文献可能为虚构或推测性内容，建议结合实际数据库验证)：
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1. **文献名称**: *FUBP3 regulates spermatogenesis through interaction with germ cell-specific RNA targets*
**作者**: Li et al. (2018)
**摘要**: 本研究利用FUBP3 (N-term)抗体进行免疫组化分析，发现FUBP3在小鼠睾丸生精细胞中高表达，并通过结合特定RNA靶标调控精子形成过程。抗体特异性通过Western blot和siRNA敲降验证。
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2. **文献名称**: *Proteomic analysis of FUBP3 in hepatocellular carcinoma progression*
**作者**: Wang et al. (2020)
**摘要**: 通过FUBP3 (N-term)抗体的免疫沉淀结合质谱分析，揭示FUBP3在肝癌细胞中与致癌信号通路相关蛋白(如β-catenin)相互作用，促进肿瘤侵袭转移。抗体特异性在多种细胞系中得到验证。
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3. **文献名称**: *Characterization of a novel FUBP3 monoclonal antibody for neurodegenerative disease research*
**作者**: Smith et al. (2021)
**摘要**: 报道一种新型FUBP3 (N-term)单克隆抗体的开发与验证，证明其在阿尔茨海默病模型脑组织中特异性识别FUBP3蛋白，并揭示FUBP3与tau蛋白病理聚集的相关性。
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4. **文献名称**: *FUBP3 modulates alternative splicing in cardiac development*
**作者**: Chen et al. (2019)
**摘要**: 使用FUBP3 (N-term)抗体进行染色质免疫共沉淀(ChIP)和免疫荧光实验，发现FUBP3通过调控心肌细胞中pre-mRNA剪接参与心脏发育缺陷的分子机制。
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**建议**：以上文献信息为示例性质，实际研究中请通过PubMed、Google Scholar等平台以“FUBP3 antibody”或“FUBP3 N-terminal”为关键词检索，并关注抗体应用相关的功能研究或技术验证类论文。
The FUBP3 (N-term) antibody is designed to target the N-terminal region of Far Upstream Element Binding Protein 3 (FUBP3), a member of the FUBP family of DNA/RNA-binding proteins. FUBP3. also known as KHSRP or MARTA1. plays a role in transcriptional and post-transcriptional gene regulation by interacting with nucleic acids and associated protein complexes. It is involved in processes such as mRNA stability, splicing, and transport, particularly in neuronal cells. The N-terminal domain of FUBP3 is critical for its functional interactions, including binding to regulatory elements in target RNAs or DNAs.
This antibody is commonly used in research applications like Western blotting, immunofluorescence, and immunoprecipitation to study FUBP3 expression, localization, and molecular interactions. Its specificity for the N-terminal region allows researchers to distinguish FUBP3 from homologous family members (e.g., FUBP1) and investigate isoform-specific functions. FUBP3 has been implicated in neurological development, cellular differentiation, and diseases such as cancer, where its dysregulation may contribute to tumor progression. Validation of the antibody typically includes testing in knockout cell lines or tissues to confirm target specificity. Studies using this reagent help elucidate FUBP3's role in gene regulatory networks and its potential as a therapeutic target.
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